Studies

Primary studies

26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.

17 studies

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StudyYearReviewsReview outcomes linkedTrial data
Apicoectomy versus apical curettage in combination with or without L-PRF application: a randomized clinical trial.
Gulsever 2025 · Gulsever Serap, Ersahan Seyda, et al. · Scientific reports
PMID:40057596
20252none statednot extracted yet
Impact of Advanced Platelet-Rich Fibrin on Early Bone Healing After Endodontic Microsurgery: A Randomized Controlled Trial.
Karkle 2025 · Karkle Aleksandra, Neimane Laura, et al. · Diagnostics (Basel, Switzerland)
PMID:40075764
202521not extracted yet
Volumetric evaluation of effects of platelet-rich fibrin and concentrated growth factor on early bone healing after endodontic microsurgery: a…
You 2023 · You Jae-Seek, Jung Gyeo-Woon, et al. · BMC oral health
PMID:37899448
20232none statednot extracted yet
Assessment of bone healing after mineral trioxide aggregate and platelet-rich fibrin application in periapical lesions using cone-beam computed…
Karan 2020 · Karan Nazife Begüm, Aricioğlu Banu · Clinical oral investigations
PMID:31321573
20202none statednot extracted yet
Pain and quality of life after endodontic surgery with or without advanced platelet-rich fibrin membrane application: a randomized clinical trial.
Soto-Peñaloza 2020 · Soto-Peñaloza David, Peñarrocha-Diago Miguel, et al. · Clinical oral investigations
PMID:31612327
202022not extracted yet
Comparative analysis of platelet-rich fibrin, platelet-rich fibrin with hydroxyapatite and platelet-rich fibrin with alendronate in bone…
Tiwari 2021 · Tiwari Urvashi Ojha, Chandra Ramesh, et al. · Journal of conservative dentistry : JCD
PMID:33623234
20202none statednot extracted yet
Two-dimensional and three-dimensional evaluation of bone regeneration using platelet-rich fibrin versus bone putty in large periapical lesions after…
Kumar 2026 · Kumar Pravin, Soundharrajan P, et al. · Journal of conservative dentistry and endodontics
PMID:41940358
20261none statednot extracted yet
Platelet rich fibrin versus hydroxyapatite in the management of periapical inflammatory lesions: A prospective clinico-radiographic comparative…
Bhardwaj 2025 · Bhardwaj Swasti, Singh Gaurav, et al. · Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
DOI:10.1016/j.ajoms.2025.03.005
20251none statednot extracted yet
PRF Membranes Enhance Postoperative Recovery After Periapical Surgery: A Single-Blind Randomized Pilot Trial Using 3D Imaging
Major 2025 · Major Martin, Polyák Melinda, et al. · Oral
DOI:10.3390/oral5040098
202511not extracted yet
Comparative evaluation of platelet-rich plasma + β-tricalcium phosphate and platelet-rich fibrin + β-tricalcium phosphate for healing periapical…
Kavitha 2024 · Kavitha Mahendran, Krishnaveni Raju, et al. · Medicine and pharmacy reports
PMID:39502761
20241none statednot extracted yet
Efficacy of mixture of injectable-platelet-rich fibrin and type-1 collagen particles on the closure of through-and-through periapical bone defects:…
Arpitha 2023 · M Arpitha, S Tewari, et al. · International endodontic journal
PMID:37418583
202311not extracted yet
Multi-modular bone healing assessment in a randomized controlled clinical trial of root-end surgery with the use of leukocyte- and platelet-rich…
Meschi 2020 · Meschi Nastaran, Vanhoenacker Anke, et al. · Clinical oral investigations
PMID:32418011
202011not extracted yet
Evaluation of Hydroxyapatite Granules, CERAMENT™, and Platelet-rich Fibrin in the Management of Endodontic Apical Surgery.
Singh 2020 · Singh Rohit, Ismail Prabu Mahin Syed, et al. · The journal of contemporary dental practice
PMID:32690839
20201none statednot extracted yet
Evaluation of healing after periapical surgery using platelet-rich fibrin and nanocrystalline hydroxyapatite with collagen in combination with…
Thanikasalam 2018 · Thanikasalam Monika, Ahamed Shafie, et al. · Endodontology
DOI:10.4103/endo.endo_55_17
20181none statednot extracted yet
Root-end surgery with leucocyte- and platelet-rich fibrin and an occlusive membrane: a randomized controlled clinical trial on patients' quality of…
Meschi 2018 · Meschi Nastaran, Fieuws Steffen, et al. · Clinical oral investigations
PMID:29524025
201811not extracted yet
A comparative clinical study to evaluate the healing of large periapical lesions using platelet-rich fibrin and hydroxyapatite
Monga 2016 · Monga Prashant, Grover Ruma, et al. · Endodontology
DOI:10.4103/0970-7212.184336
20161none statednot extracted yet
Effect of Platelet-rich Fibrin on Healing of Apicomarginal Defects: A Randomized Controlled Trial.
Dhiman 2015 · Dhiman Meenu, Kumar Suresh, et al. · Journal of endodontics
PMID:25963290
201511not extracted yet