Primary study · included by 5 reviews

Randomised controlled trial of arthrocentesis with or without PRF for internal derangement of the TMJ.

Karadayi 2021 · Karadayi Ugur, Gursoytrak Burcu · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery · 2021

Included by

Effectiveness of Platelet-Rich Fibrin for Temporomandibular Disorders Management: A Systematic and Meta-Analysis.

Non-Cochrane · intervention · 2026 · cited as Karadayi 2021 · Fig. 3 and Fig. 4 forest plots; Supplementary Table 2; reference list

The review does not say which of its outcomes this study informs.

Advanced, pharmacological and complementary interventions for chronic or recurrent orofacial pain conditions: a systematic evidence map with selective meta-analyses.

Non-Cochrane · intervention · 2026 · cited as Karadayi 2021 · Reference list [174]

The review does not say which of its outcomes this study informs.

Efficacy and Safety of Intra-Articular Therapies for Temporomandibular Disorders: A Systematic Review and Meta-Analysis.

Non-Cochrane · intervention · 2026 · cited as Karadayi 2021 · Supplement S2; reference list

The review does not say which of its outcomes this study informs.

Effectiveness of arthrocentesis versus other therapeutic modalities in patients with temporomandibular disorders. Systematic review and meta-analysis.

Non-Cochrane · intervention · 2026 · cited as Karadayi 2021 · Table 1; Figures 4-8; reference 38

Outcome this study informs	Pooled effect	Evidence	Certainty
Pain intensity (VAS) Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols	Meta-regression coefficient (beta) -1.609 [-5.033, 1.816]	NR	GRADE not reported
Maximum incisal opening (MIO) TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)	SMD -2.93 [-4.54, -1.32]	11 studies · 325 participants	Very low
Maximum incisal opening (MIO) Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols	Meta-regression coefficient (beta) -1.640 [-24.881, 21.602]	NR	GRADE not reported
Pain intensity (VAS) TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)	MD -0.25 [-1.09, 0.59]	26 studies · 947 participants	Very low
Maximum incisal opening (MIO) Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols	Meta-regression coefficient (beta) 0.302 [-0.231, 0.836]	NR	GRADE not reported
Pain intensity (VAS) Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols	Meta-regression coefficient (beta) -0.028 [-0.125, 0.069]	NR	GRADE not reported

Comparative efficacy of arthrocentesis combined with different drug injections for arthrogenic temporomandibular disorders: a network meta-analysis of randomized trials.

Non-Cochrane · intervention · 2026 · cited as Karadayi 2021 · Table 1; reference 24

The review does not say which of its outcomes this study informs.

5 including reviews in total.