Primary study · included by 4 reviews

Is arthrocentesis plus platelet-rich plasma superior to arthrocentesis plus hyaluronic acid for the treatment of temporomandibular joint osteoarthritis: a randomized clinical trial.

Kilic 2016 · Cömert Kiliç S, Güngörmüş M · International journal of oral and maxillofacial surgery · 2016

Included by

The review does not say which of its outcomes this study informs.

Efficacy and Safety of Intra-Articular Therapies for Temporomandibular Disorders: A Systematic Review and Meta-Analysis.
Non-Cochrane · intervention · 2026 · cited as Comert Kilic and Gungormus 2016b · Supplement S2; reference list

The review does not say which of its outcomes this study informs.

Effectiveness of arthrocentesis versus other therapeutic modalities in patients with temporomandibular disorders. Systematic review and meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Comert Kilic 2016 A · Table 1; Figures 4-8; reference 24
Outcome this study informsPooled effectEvidenceCertainty
Mandibular movement: protrusive
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -0.021 [-0.501, 0.460]NRGRADE not reported
Lateral movement (only lateral)
TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)
MD -0.52 [-1.13, 0.09]5 studies · 145 participantsGRADE not reported
Mandibular movement: protrusive
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -15.246 [-134.135, 103.644]NRGRADE not reported
Maximum incisal opening (MIO)
TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)
SMD -2.93 [-4.54, -1.32]11 studies · 325 participantsVery low
Overall mandibular movement
TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)
MD -0.40 [-0.93, 0.14]22 studies · 796 participantsVery low
Mandibular movement: lateral only
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -37.690 [-117.923, 42.706]NRGRADE not reported
Maximum incisal opening (MIO)
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -1.640 [-24.881, 21.602]NRGRADE not reported
Mandibular movement: lateral only
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) 0.160 [0.056, 0.263]NRGRADE not reported
Masticatory efficiency
TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)
MD 1.15 [0.22, 2.08]2 studies · 55 participantsVery low
Protrusive movement
TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)
MD 0.01 [-0.99, 1.02]6 studies · 190 participantsGRADE not reported
Maximum incisal opening (MIO)
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) 0.302 [-0.231, 0.836]NRGRADE not reported

The review does not say which of its outcomes this study informs.

4 including reviews in total.