Non-Cochrane · intervention · PM42144881
Functional Outcomes of Prosthetic Rehabilitation in Older Adults With Tooth Loss: A Systematic Review and Meta-Analysis.
Molinero-Mourelle Pedro, Bell Azize, Chebib Najla, et al. · Gerodontology · 2026 · PubMed · doi:10.1111/ger.70078
Findings
Population Older adults aged 65 years or older with tooth loss wearing dental prostheses for at least 6 months
10 findings
| Implant-supported prostheses (implant overdentures and fixed full-arch implant prostheses) | Pre-treatment baseline (within-group change) | Objective masticatory performance (colour-mixing gum, SDHue; lower is better) 6-12 months follow-up | SMD -0.033 [-0.824, 0.759] GRADE not reported 2 studies |
| Implant-supported prostheses (implant overdentures and fixed full-arch implant prostheses) | Pre-treatment baseline (within-group change) | OHRQoL (OHIP-20; lower is better) 6-12 months follow-up | SMD -1.007 [-1.358, -0.656] GRADE not reported 2 studies |
| Implant-supported prostheses (implant overdentures and fixed full-arch implant prostheses) | Pre-treatment baseline (within-group change) | Objective masticatory performance (colour-mixing gum, SDHue; lower is better) >12 months follow-up | SMD -0.601 [-0.945, -0.256] GRADE not reported 2 studies |
| Implant-supported prostheses (implant overdentures and fixed full-arch implant prostheses) | Pre-treatment baseline (within-group change) | Maximum bite force (Occlusal Force-Meter GM10) >12 months follow-up | SMD 1.124 [0.719, 1.529] GRADE not reported 2 studies |
| Implant-supported prostheses (implant overdentures and fixed full-arch implant prostheses) | Pre-treatment baseline (within-group change) | OHRQoL (OHIP-14; lower is better) >12 months follow-up | SMD -2.612 [-6.250, 1.026] GRADE not reported 2 studies |
| Implant-supported prostheses (implant overdentures and fixed full-arch implant prostheses) | No comparison (pooled follow-up mean) | Subjective masticatory ability (VAS 0-100 mm) 6-12 months follow-up | MEAN 90.571 [75.304, 105.838] GRADE not reported 2 studies |
| Implant-supported prostheses (implant overdentures and fixed full-arch implant prostheses) | Pre-treatment baseline (within-group change) | Maximum bite force (Occlusal Force-Meter GM10) 6-12 months follow-up | SMD 0.668 [0.142, 1.193] GRADE not reported 2 studies |
| Implant-supported prostheses (implant overdentures and fixed full-arch implant prostheses) | Pre-treatment baseline (within-group change) | OHRQoL (OHIP-14; lower is better) 6-12 months follow-up | SMD -2.550 [-4.637, -0.463] GRADE not reported 3 studies |
| Non-implant-supported prostheses (conventional or digital complete dentures, partial dentures) | Pre-treatment baseline (within-group change) | OHRQoL (OHIP-20; lower is better) 6-12 months follow-up | SMD -0.948 [-2.007, 0.111] GRADE not reported 3 studies |
| Non-implant-supported prostheses (conventional or digital complete dentures, partial dentures) | No comparison (pooled follow-up mean) | Subjective masticatory ability (VAS 0-100 mm) 6-12 months follow-up | MEAN 76.700 [64.558, 88.842] GRADE not reported 3 studies |
Included primary studies 24
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Muller 2013 Implant-supported mandibular overdentures in very old adults: a randomized controlled trial. PMID:24158342 | 2013 | 3 other reviews | Objective masticatory performance (colour-mixing gum, SDHue; lower is better); Maximum bite force (Occlusal Force-Meter GM10); Subjective masticatory ability (VAS 0-100 mm); OHRQoL (OHIP-20; lower is better); PM42144881-P1-O8 | not extracted yet |
| Ayna 2018 A comparative study on 7-year results of "All-on-Four™" immediate-function concept for completely edentulous mandibles: metal-ceramic vs.… PMID:28321585 | 2018 | 1 other review | OHRQoL (OHIP-14; lower is better); PM42144881-P1-O6; PM42144881-P1-O7 | not extracted yet |
| Carletti 2019 Prostheses satisfaction and diet of elderly wearing a single implant overdenture: A six-month assessment. PMID:31368121 | 2019 | 1 other review | Subjective masticatory ability (VAS 0-100 mm); OHRQoL (OHIP-20; lower is better) | not extracted yet |
| Casucci 2025 Digital vs. conventional removable complete dentures: A retrospective study on clinical effectiveness and cost-efficiency in edentulous… PMID:39645185 | 2025 | 1 other review | not stated | not extracted yet |
| Berretin-Felix 2008 A longitudinal study of quality of life of elderly with mandibular implant-supported fixed prostheses. PMID:18565012 | 2008 | this review only | OHRQoL (OHIP-14; lower is better); PM42144881-P1-O6; PM42144881-P1-O7 | not extracted yet |
| Bressan 2012 Implant-supported mandibular overdentures: a cross-sectional study. PMID:21631597 | 2012 | this review only | not stated | not extracted yet |
| Brigido 2025 Influence of prosthodontic rehabilitation and dietary advice on glycaemic control, nutritional status and oral health-related quality of… PMID:38995836 | 2025 | this review only | not stated | not extracted yet |
| Dable 2013 Assessment of Oral Health Related Quality of Life Among Completely Edentulous Patients in Western India by Using GOHAI. PMID:24179944 | 2013 | this review only | not stated | not extracted yet |
| Emami 2010 Better oral health related quality of life: type of prosthesis or psychological robustness? PMID:19931345 | 2010 | this review only | not stated | not extracted yet |
| Enkling 2019 A prospective cohort study on survival and success of one-piece mini-implants with associated changes in oral function: Five-year outcomes. PMID:31021481 | 2019 | this review only | Objective masticatory performance (colour-mixing gum, SDHue; lower is better); Maximum bite force (Occlusal Force-Meter GM10); Subjective masticatory ability (VAS 0-100 mm); OHRQoL (OHIP-14; lower is better) | not extracted yet |
| Geckili 2011 Impact of mandibular two-implant retained overdentures on life quality in a group of elderly Turkish edentulous patients. PMID:21183231 | 2011 | this review only | OHRQoL (OHIP-14; lower is better); PM42144881-P1-O6 | not extracted yet |
| Goncalves 2024 Four-year assessment of masticatory function in mandibular overdenture wearers: A randomised clinical trial comparing two to four implants… PMID:38873742 | 2024 | this review only | not stated | not extracted yet |
| Heydecke 2003 Oral and general health-related quality of life with conventional and implant dentures. PMID:12752541 | 2003 | this review only | OHRQoL (OHIP-20; lower is better); PM42144881-P1-O8 | not extracted yet |
| Heydecke 2004 Complete dentures and oral health-related quality of life -- do coping styles matter? PMID:15239781 | 2004 | this review only | not stated | not extracted yet |
| Iwaki 2024 Effect of digital complete dentures manufactured using the custom disk method on masticatory function. PMID:38192789 | 2024 | this review only | not stated | not extracted yet |
| Kawai 2017 A double blind randomized clinical trial comparing lingualized and fully bilateral balanced posterior occlusion for conventional complete… PMID:27474364 | 2017 | this review only | Subjective masticatory ability (VAS 0-100 mm) | not extracted yet |
| Maniewicz 2019 Effect of implant-supported mandibular overdentures versus reline on masticatory performance and salivary flow rates in very old adults-A… PMID:30500094 | 2019 | this review only | Objective masticatory performance (colour-mixing gum, SDHue; lower is better); Maximum bite force (Occlusal Force-Meter GM10); OHRQoL (OHIP-14; lower is better) | not extracted yet |
| Martin-Ares 2016 Prosthetic hygiene and functional efficacy in completely edentulous patients: satisfaction and quality of life during a 5-year follow-up. PMID:25893901 | 2016 | this review only | not stated | not extracted yet |
| Policastro 2020 Influence of the height of the mandibular ridge on the masticatory function during the functional adaptation with new complete dentures. PMID:33111881 | 2020 | this review only | not stated | not extracted yet |
| Schuster 2020 Immediate vs conventional loading of Facility-Equator system in mandibular overdenture wearers: 1-year RCT with clinical, biological, and… PMID:32363765 | 2020 | this review only | OHRQoL (OHIP-20; lower is better) | not extracted yet |
| Singla 2025 Impact of Soft Liners on Bite Force in Complete Denture Wearers: A Prospective Cohort Study. PMID:40013230 | 2025 | this review only | not stated | not extracted yet |
| Suzuki 2019 Influence of simplified dietary advice combined with new complete denture fabrication on masticatory function of complete denture wearers. PMID:31228219 | 2019 | this review only | not stated | not extracted yet |
| Thomason 2003 Patient satisfaction with mandibular implant overdentures and conventional dentures 6 months after delivery. PMID:14651229 | 2003 | this review only | Subjective masticatory ability (VAS 0-100 mm); OHRQoL (OHIP-20; lower is better) | not extracted yet |
| Zhang 2019 Patient-reported outcome measures (PROMs) and maintenance events in 2-implant-supported mandibular overdenture patients: A 5-year… PMID:30714227 | 2019 | this review only | not stated | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Older adults (mean age 65 years or above) with partial or complete tooth loss wearing any type of dental prosthesis for at least 6 months | Older adults with mean ages 65.8 to 85.0 years, mostly edentulous (n=24 studies) |
| Intervention | Prosthodontic treatment: removable partial or complete conventional dentures, fixed and removable implant prostheses, digitally manufactured dentures | Complete dentures, implant overdentures, fixed full-arch implant prostheses, removable partial dentures, digital dentures |
| Comparison | No predefined comparator (comparison groups considered for subgroup analysis) | Baseline (within-group pre-post change); some studies compared complete dentures with implant overdentures |
| Outcomes | Masticatory performance, masticatory ability, maximum bite force, swallowing and speech, OHRQoL, denture satisfaction, comfort | Masticatory performance (SDHue), maximum bite force, subjective masticatory ability (VAS), OHIP-14, OHIP-20, OHIP-EDENT, OIDP, GOHAI, satisfaction and comfort |
| Study designs | RCTs, non-randomized controlled trials, case series, cross-sectional, cohort and case-control studies | 9 RCTs, 1 non-randomized trial, 6 cohort studies, 4 cross-sectional studies, 6 case series; 12 studies in meta-analysis |
| Timing | Follow-up of at least 6 months; short term 6-12 months, long term more than 12 months | 6-12 months and more than 12 months |
AMSTAR 2 items
Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.
| Item | Extractor A | Extractor B | Agree |
|---|---|---|---|
| 1Research question includes PICO components | Yes | Yes | yes |
| 2Protocol established before the reviewcritical | Partial Yes | Partial Yes | yes |
| 3Choice of study designs explained | Yes | Yes | yes |
| 4Comprehensive literature searchcritical | Partial Yes | Partial Yes | yes |
| 5Study selection in duplicate | Yes | Yes | yes |
| 6Data extraction in duplicate | No | No | yes |
| 7List of excluded studies with reasonscritical | No | No | yes |
| 8Included studies described in detail | Partial Yes | Yes | no |
| 9Risk of bias assessed satisfactorilycritical | RCT: Yes · NRSI: Partial Yes | NRSI: Partial Yes · RCT: Yes | no |
| 10Funding of included studies reported | No | No | yes |
| 11Appropriate meta-analysis methodscritical | RCT: No · NRSI: Partial Yes | NRSI: No · RCT: No | no |
| 12Impact of risk of bias on the pooled results | No | No | yes |
| 13Risk of bias accounted for in interpretationcritical | No | No | yes |
| 14Heterogeneity explained | Yes | Yes | yes |
| 15Publication bias investigatedcritical | No | No | yes |
| 16Conflicts of interest reported | Yes | Yes | yes |
| Overall | Critically Low | Critically Low | yes |