Non-Cochrane · prognostic · PM41869868
Prevalence of Hypercementosis in Radiographic Studies: A Systematic Review and Meta-Analysis With Clinical Implications for Endodontic Assessment.
Segura-Raya Carlos, Diaz-Flores Víctor, Martín-Jiménez Milagros, et al. · International endodontic journal · 2026 · PubMed · doi:10.1111/iej.70147
Findings
Population Dentate human populations
20 findings
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Crude sample-size-weighted proportion from aggregated counts (not meta-analytic) | Prevalence (%) 3.76 [3.46, 4.07] GRADE not reported 10 studies · 14881 participants |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Leave-one-out sensitivity analysis omitting Luke 2017 | Prevalence (%) 3.45 [1.67, 6.99] GRADE not reported 9 studies |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Tooth-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Leave-one-out sensitivity analysis omitting Burklein 2012 | Prevalence (%) 0.37 [0.06, 2.39] GRADE not reported 2 studies |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Leave-one-out sensitivity analysis omitting Patil 2018 | Prevalence (%) 3.78 [1.87, 7.49] GRADE not reported 9 studies |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Tooth-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Leave-one-out sensitivity analysis omitting Eren 2017 | Prevalence (%) 0.34 [0.04, 2.61] GRADE not reported 2 studies |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Leave-one-out sensitivity analysis omitting Haghanifar 2019 | Prevalence (%) 5.65 [3.56, 8.87] GRADE not reported 9 studies |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Leave-one-out sensitivity analysis omitting Burklein 2012 | Prevalence (%) 4.40 [2.28, 8.32] GRADE not reported 9 studies |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Leave-one-out sensitivity analysis omitting Eren 2017 | Prevalence (%) 4.11 [2.11, 7.86] GRADE not reported 9 studies |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Leave-one-out sensitivity analysis omitting Elsayed 2019 | Prevalence (%) 3.44 [1.61, 7.20] GRADE not reported 9 studies |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Tooth-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Overall (all imaging modalities) | Prevalence (%) 0.25 [0.06, 1.00] GRADE not reported 3 studies · 52666 participants |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Leave-one-out sensitivity analysis omitting Malik 2021 | Prevalence (%) 3.65 [1.80, 7.29] GRADE not reported 9 studies |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Overall (all imaging modalities) Unresolved: the two extractors disagree on this row. | Prevalence (%) 3.89 [2.04, 7.30] Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness 10 studies · 14881 participants |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Tooth-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Leave-one-out sensitivity analysis omitting Patil 2018 | Prevalence (%) 0.13 [0.10, 0.17] GRADE not reported 2 studies |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Leave-one-out sensitivity analysis omitting Escuza Gonzalez 2025 | Prevalence (%) 4.33 [2.23, 8.26] GRADE not reported 9 studies |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Tooth-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Crude sample-size-weighted proportion from aggregated counts (not meta-analytic) | Prevalence (%) 0.203 [0.165, 0.242] GRADE not reported 3 studies · 52666 participants |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Leave-one-out sensitivity analysis omitting Defne 2021 | Prevalence (%) 3.39 [1.53, 7.32] GRADE not reported 9 studies |
| Radiographic assessment (periapical, panoramic or CBCT) | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Leave-one-out sensitivity analysis omitting Bernal Ruiz 2023 | Prevalence (%) 3.24 [1.58, 6.52] GRADE not reported 9 studies |
| Periapical radiography | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Subgroup: periapical radiography | Prevalence (%) 2.92 [0.57, 13.66] GRADE not reported 2 studies · 1250 participants |
| Cone-beam computed tomography (CBCT) | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Subgroup: CBCT | Prevalence (%) 3.44 [1.74, 6.67] GRADE not reported 2 studies · 1794 participants |
| Panoramic radiography | Not applicable (single-group prevalence) | Patient-level prevalence of hypercementosis Radiographic archives and clinic samples, mostly single center · Subgroup: panoramic radiography | Prevalence (%) 4.46 [1.93, 9.97] GRADE not reported 6 studies · 11837 participants |
Included primary studies 11
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Malik 2021 matched by author and year (probable) | NR | 1 other review | Patient-level prevalence of hypercementosis | not extracted yet |
| Bernal Ruiz 2023 Patrones de hipercementosis y su relación con posibles factores etiológicos locales en radiografías de individuos de una población mexicana DOI:10.21142/2523-2754-1103-2023-163 | 2023 | this review only | Patient-level prevalence of hypercementosis | not extracted yet |
| Bernal Ruiz 2023 [Patterns of hypercementosis and their relationship with possible local etiological factors in radiographs of individuals from a mexican… PMID:38287996 | 2023 | this review only | Patient-level prevalence of hypercementosis | not extracted yet |
| Bürklein 2012 Occurrence of hypercementosis in a German population. PMID:23146646 | 2012 | this review only | Patient-level prevalence of hypercementosis; Tooth-level prevalence of hypercementosis | not extracted yet |
| Defne 2021 Prevalence of hypercementosis and frequency of possible etiological factors in a Turkish subpopulation. PMID:33851668 | 2021 | this review only | Patient-level prevalence of hypercementosis | not extracted yet |
| Elsayed 2019 Radiographic evaluation and determination of hypercementosis patterns in Al-Madinah Al-Munawwarah, Saudi Arabia: A retrospective… PMID:31293261 | 2019 | this review only | Patient-level prevalence of hypercementosis | not extracted yet |
| Eren 2017 Evaluation of the frequency and characteristics of hypercementosis in the turkish population with cone-beam computed tomography. PMID:28656927 | 2017 | this review only | Patient-level prevalence of hypercementosis; Tooth-level prevalence of hypercementosis | not extracted yet |
| Escuza Gonzalez 2025 [Prevalence of dental anomalies in panoramic radiographs of patients aged 10 to 30 from a radiographic center: a cross-sectional study]. PMID:40231105 | 2025 | this review only | Patient-level prevalence of hypercementosis | not extracted yet |
| Haghanifar 2019 Radiographic Evaluation of Dental Anomaly Prevalence in a Selected Iranian Population. PMID:31214635 | 2019 | this review only | Patient-level prevalence of hypercementosis | not extracted yet |
| Luke 2017 Both the 5' untranslated region and the sequences surrounding the start site contribute to efficient initiation of translation in vitro. PMID:2017171 | 1991 | this review only | Patient-level prevalence of hypercementosis | not extracted yet |
| Patil 2018 matched by author and year (probable) | NR | this review only | Patient-level prevalence of hypercementosis; Tooth-level prevalence of hypercementosis | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
| Review | Shared studies | Jaccard |
|---|---|---|
| Evaluating calcineurin inhibitors as alternatives to steroids in treating Oral Lichen Planus: a systematic review and meta-analysis. (2026) | 1 | 0.01 |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Dentate human populations, any age, sex or geography | Dentate patients in 10 cross-sectional studies (14881 patients; 52666 teeth in 3 studies), from Asia, Europe and Hispanic America |
| Intervention | Not applicable (prevalence review; condition: hypercementosis) | Not applicable |
| Comparison | Not applicable | Not applicable |
| Outcomes | Prevalence of hypercementosis diagnosed on periapical radiographs, panoramic radiographs or CBCT (patient and tooth level) | Patient-level pooled prevalence 3.9% (10 studies); tooth-level pooled prevalence 0.25% (3 studies) |
| Study designs | Cross-sectional studies reporting quantitative prevalence data | 10 cross-sectional radiographic studies (n=10) |
| Timing | Not specified | Not specified |