Non-Cochrane · prognostic · PM41319107
Preoperative Periapical Status and Outcomes of Vital Pulp Therapy: A Systematic Review and Meta-Analysis.
Basso Isadora de Souza, Dotto Laura Huffel, Kopper Patrícia Maria Poli, et al. · Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026 · PubMed · doi:10.1111/aej.70042
Findings
Population Teeth with exposed vital pulps undergoing full pulpotomy (permanent teeth)
1 finding
| Preoperative periapical radiolucency/ligament widening (periapical alteration present) | No preoperative periapical radiographic alteration | Success of full pulpotomy (healed vs failed cases) Follow-up 1 to 6 years | OR 0.75 [0.30, 1.87] Low Downgraded: risk of bias, imprecision, inconsistency 5 studies · 1477 participants |
Included primary studies 6
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Asgary 2022 Outcomes of root canal therapy or full pulpotomy using two endodontic biomaterials in mature permanent teeth: a randomized controlled trial. PMID:34854987 | 2022 | 3 other reviews | Success of full pulpotomy (healed vs failed cases) | not extracted yet |
| Asgary 2014 Five-year results of vital pulp therapy in permanent molars with irreversible pulpitis: a non-inferiority multicenter randomized clinical… PMID:24771228 | 2015 | this review only | Success of full pulpotomy (healed vs failed cases) | not extracted yet |
| Asgary 2024 Outcomes and predictive factors of vital pulp therapy in a large-scale retrospective cohort study over 10 years. PMID:38267594 | 2024 | this review only | Success of full pulpotomy (healed vs failed cases) | not extracted yet |
| Elmas 2023 Two-year Outcomes of Coronal Pulpotomy in Young Permanent Molars with Clinical Signs Indicative of Irreversible Pulpitis. PMID:36879376 | 2023 | this review only | Success of full pulpotomy (healed vs failed cases) | not extracted yet |
| Qudeimat 2016 Mineral trioxide aggregate pulpotomy for permanent molars with clinical signs indicative of irreversible pulpitis: a preliminary study. PMID:26841969 | 2017 | this review only | Success of full pulpotomy (healed vs failed cases) | not extracted yet |
| Taha 2024 Outcome and Prognostic Factors for Partial and Full Pulpotomy in the Management of Spontaneous Symptomatic Pulpitis in Carious Mature… PMID:38583758 | 2024 | this review only | not stated | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Participants with permanent teeth undergoing vital pulp therapy | Permanent teeth with carious pulp exposure undergoing full or partial pulpotomy (n=6 studies; 5 meta-analyzed, 1477 teeth) |
| Intervention | Periapical radiographic status on the day of treatment | Preoperative periapical radiolucency or periodontal ligament widening |
| Comparison | Gender, age, systemic condition, preoperative symptoms/diagnosis, caries extent/location, restoration extent/type, bleeding time | No preoperative periapical alteration |
| Outcomes | Clinical and radiographic success and survival | Full pulpotomy success (healed versus failed cases) |
| Study designs | Clinical trials and observational studies | Randomised trials and prospective and retrospective cohort studies |
| Timing | Data collected immediately before the procedure; follow-up at least one year | Follow-up 1 to 6 years |