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Evidence found and GRADE certainty

5 questions · 5 findings · 1 reviews · Sexually Transmitted Infections

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No studies found 2 · 40%GRADE not reported 1 · 20%Very low 0 · 0%Low 0 · 0%Moderate 1 · 20%High 1 · 20%

Antibiotic treatment (benzathine penicillin) vs other antibiotics

Serological cure (4‐fold decrease or greater in non‐treponemal tests titre) · newborns with congenital syphilis

Antibiotic treatment (benzathine penicillin) showed no clear difference in serological cure (4‐fold decrease or greater in non‐treponemal tests… compared with any other antibiotic (procaine benzylpenicillin) (moderate certainty).

1 finding from 1 review

Antibiotic treatment (benzathine penicillin) vs other antibiotics

Absence of clinical manifestations of congenital syphilis during · newborns with congenital syphilis

Antibiotic treatment (benzathine penicillin) showed no clear difference in absence of clinical manifestations of congenital syphilis during compared with any other antibiotic (procaine benzylpenicillin) (high certainty).

1 finding from 1 review