Very early treatment showed no clear difference in chronic lung disease compared with expectant management (low certainty).
Very early treatment showed no clear difference in severe Intraventricular hemorrhage (grades III and IV) compared with expectant management (moderate certainty).
Very early treatment showed no clear difference in necrotizing enterocolitis (NEC; stage 2 or greater) compared with expectant management (moderate certainty).
Very early treatment showed no clear difference in neurodevelopmental outcomes (moderate/severe cognitive delay at 18… compared with expectant management (low certainty).
Very early treatment showed no clear difference in neurodevelopmental outcomes (moderate/severe motor delay at 18 to 24… compared with expectant management (low certainty).
Very early treatment showed no clear difference in neurodevelopmental outcomes (moderate/severe language delay at 18 to… compared with expectant management (low certainty).
Very early treatment showed no clear difference in all‐cause mortality during hospital stay compared with expectant management (moderate certainty).
Very early treatment showed no clear difference in proportion of infants requiring surgical PDA ligation or… compared with expectant management (moderate certainty).
It is very uncertain whether very early treatment changes proportion of infants receiving any pharmacotherapy for a… compared with expectant management (very low certainty).
Very early discharge may leads to lower treatment failure; death compared with early discharge (low certainty).
Very early discharge may leads to lower duration of total antimicrobial treatment compared with early discharge (low certainty).
Very early discharge may leads to lower duration of intravenous antimicrobial treatment compared with early discharge (low certainty).
Very early discharge may leads to lower duration of oral antimicrobial treatment compared with early discharge (low certainty).
Very early discharge showed no clear difference in treatment failure; rehospitalization or adjustment of antimicrobial… compared with early discharge (low certainty).
Very early discharge showed no clear difference in treatment failure; rehospitalization or adjustment of antimicrobial… compared with early discharge (low certainty).
It is very uncertain whether prophylactic or very early CPAP changes failed treatment defined as recurrent apnoea, hypoxia, hypercarbia… compared with supportive care (very low certainty).
Specialised early intervention (SEI) may leads to higher global state: recovery (assessed by proportion recovered, as defined… compared with treatment (low certainty).
Early discharge showed no clear difference in treatment failure; rehospitalization or adjustment of antimicrobial… compared with non‐early discharge (low certainty).
Early discharge may leads to lower treatment failure; death compared with non‐early discharge (low certainty).