Findings

What do systematic reviews say?

8 questions · 8 findings · 4 reviews · Pregnancy and Childbirth

Sort:Best matchNewest Highest certainty Download CSV

No studies found 2 · 25%GRADE not reported 1 · 12.5%Very low 3 · 37.5%Low 1 · 12.5%Moderate 0 · 0%High 1 · 12.5%

Intrauterine balloon tamponade (condom‐loaded catheter) vs uterovaginal packing (intrauterine tamponade versus another intrauterine tamponade method)

Hysterectomy to control bleeding · Women (aged between 20 and 40) diagnosed with primary PPH following 'normal' vaginal birth and unresponsive to medical treatment (Ashraf…

The review found no eligible studies for this question.

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotic prophylaxis vs no treatment or placebo

Incidence of severe maternal infectious morbidity · Women who had normal vaginal births

1 finding from 1 review

Routine antibiotic prophylaxis after normal vaginal birth for reducing maternal infectious morbidity 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intrauterine balloon tamponade plus normal care (misoprostol) vs normal care (misoprostol)

Hysterectomy to control bleeding · women diagnosed with primary PPH following vaginal birth. Women were suspected to have PPH due to clinical atony and who were quote:…

It is very uncertain whether intrauterine balloon tamponade plus normal care (misoprostol) changes hysterectomy to control bleeding compared with normal care (misoprostol) (very low certainty).

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
RR 4.14 [0.48, 35.93]
1 study · 116 participants
Very low

External uterine compression (all methods) plus normal care vs normal care

Hysterectomy to control bleeding · women diagnosed with primary PPH following vaginal birth. PPH was defined as quote: "blood loss > 500mL after delivery" p 601

The review found no eligible studies for this question.

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intrauterine balloon tamponade (latex balloon inflated with air) plus cerclage and normal care vs normal care

Hysterectomy to control bleeding · women with PPH, due to atony, following vaginal birth at home or in hospital (Soltan 2007)

It is very uncertain whether intrauterine balloon tamponade (latex balloon inflated with air)… changes hysterectomy to control bleeding compared with normal care (very low certainty).

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
RR 0.14 [0.01, 2.74]
1 study · 240 participants
Very low

Bakri balloon tamponade vs condom‐loaded Foley Catheter (one intrauterine tamponade compared to another intrauterine tamponade technique)

Hysterectomy to control bleeding · women with primary atonic postpartum haemorrhage following vaginal delivery

It is very uncertain whether bakri balloon tamponade changes hysterectomy to control bleeding compared with condom‐loaded Foley Catheter (one intrauterine tamponade compared to… (very low certainty).

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
RR 0.5 [0.05, 5.25]
1 study · 66 participants
Very low

Standard care plus IV tranexamic acid vs placebo or usual care

Hysterectomy to control bleeding · women with primary postpartum haemorrhage following vaginal or caesarean birth

Standard care plus IV tranexamic acid showed no clear difference in surgical intervention to control bleeding: Hysterectomy compared with placebo or standard care alone (high certainty).

1 finding from 1 review

Antifibrinolytic drugs for treating primary postpartum haemorrhage 2018 · Cochrane Headline outcomes only
RR 0.95 [0.81, 1.12]
1 study · 20017 participants
High

Tranexamic acid vs placebo/no treatment

Serious maternal morbidity or death · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage

1 finding from 1 review

Tranexamic acid for preventing postpartum haemorrhage 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1511 participants
Low