Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

117 questions · 119 findings · 9 reviews · Headline outcomes only

No studies found 25 · 21%GRADE not reported 14 · 11.8%Very low 29 · 24.4%Low 27 · 22.7%Moderate 16 · 13.4%High 8 · 6.7%

Topical treatments vs breastfeeding advice

Incidence of mastitis within 6 months postpartum · postpartum breastfeeding women

Topical treatments showed no clear difference in incidence of mastitis within 6 months postpartum ‐ Fusidic acid… compared with breastfeeding advice (low certainty).

2 findings from 1 review

Tranexamic acid vs placebo + standard care

Control of epistaxis: episodes of re‐bleeding over 10 days All treatments (topical and oral) · adults with nasal haemorrhage (epistaxis)

Tranexamic acid probably leads to lower control of epistaxis: episodes of re‐bleeding over 10 days All… compared with placebo plus usual care or usual care alone (moderate certainty).

1 finding from 1 review

Minoxidil vs placebo

Short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of · adults with alopecia areata

It is very uncertain whether summary of findings table ‐ Topical hair growth stimulants (minoxidil) changes short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of compared with placebo (very low certainty).

1 finding from 1 review