Global outcome (good or excellent improvement in symptoms or signs, or both) · people with eczema
Topical steroid plus topical antibiotic showed no clear difference in global outcome (good or excellent improvement in symptoms or signs,… compared with topical steroid (low certainty).
1 finding from 1 review
Change from baseline in quality of life IDQoL ranges from 0 to 30 with higher values indicating more impaired quality of life · people with eczema
1 finding from 1 review
Withdrawals due to adverse events · people with eczema
It is very uncertain whether topical steroid plus topical antibiotic changes adverse events requiring withdrawal from treatment compared with topical steroid (very low certainty).
1 finding from 1 review
Minor adverse events not leading to withdrawal of treatment · people with eczema
It is very uncertain whether topical steroid plus topical antibiotic changes minor adverse events not requiring withdrawal from treatment compared with topical steroid (very low certainty).
1 finding from 1 review
Microbiology Emergence of resistant organisms · people with eczema
1 finding from 1 review
Global change in composite ratings scale EASI ranges from 0 to 72, objective SCORAD ranges from 0 to 83 and SCORAD ranges from 0 to 108, with higher values indicating greater severity. · people with eczema
1 finding from 1 review
No of participants in whom S. aureus was isolated · people with eczema
Topical steroid plus topical antibiotic probably leads to lower no of participants in whom S. aureus was isolated compared with topical steroid (moderate certainty).
1 finding from 1 review
Change in severity · infantile seborrhoeic dermatitis (including cradle cap)
1 finding from 1 review
Adverse events · infantile seborrhoeic dermatitis (including cradle cap)
1 finding from 1 review
Quality of life · infantile seborrhoeic dermatitis (including cradle cap)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mode of delivery (risk for either assisted or cesarean delivery) · pregnant women
Topical corticosteroids may leads to higher mode of delivery (risk for either assisted or cesarean delivery) compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 1.04
9904 participants
Low
Congenital abnormality · pregnant women
Topical corticosteroids may leads to lower congenital abnormality compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.82
9433 participants
Low
Orofacial cleft · pregnant women
Topical corticosteroids may leads to higher orofacial cleft compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 1.12
40605 participants
Low
Low birthweight · pregnant women
It is very uncertain whether topical corticosteroids changes low birth weight compared with no topical corticosteroids (very low certainty).
1 finding from 1 review
RR 1.08
59419 participants
Very low
Preterm birth · pregnant women
Topical corticosteroids may leads to lower preterm delivery compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.93
59419 participants
Low
Foetal death · pregnant women
It is very uncertain whether topical corticosteroids changes foetal death compared with no topical corticosteroids (very low certainty).
1 finding from 1 review
RR 1.02
63885 participants
Very low
Low Apgar score · pregnant women
Topical corticosteroids may leads to lower low Apgar score compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.84
9220 participants
Low
Low birthweight · pregnant women
Mild/moderate topical corticosteroids may leads to lower low birth weight compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.9
55713 participants
Low
Preterm birth · pregnant women
Mild/moderate topical corticosteroids may leads to lower preterm delivery compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.88
55713 participants
Low
Foetal death · pregnant women
Mild/moderate topical corticosteroids may leads to lower foetal death compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.7
48749 participants
Low