Question · asked by 1 review

Topical antibiotics with steroids vs topical steroid: Minor adverse events not leading to withdrawal of treatment

Population
people with eczema
Intervention
Topical antibiotics with steroids
Comparison
topical steroid
Outcome
Minor adverse events not leading to withdrawal of treatment

It is very uncertain whether topical steroid plus topical antibiotic changes minor adverse events not requiring withdrawal from treatment compared with topical steroid (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Topical steroid plus topical antibiotic vs topical steroid
Minor adverse events not requiring withdrawal from treatment · children and adults with eczema
It is very uncertain whether topical steroid plus topical antibiotic changes minor adverse events not requiring withdrawal from treatment compared with topical steroid (very low certainty).
Interventions to reduce Staphylococcus aureus in the management of eczema (2019) · Cochrane Headline outcomes only
RR 0.3 [0.12, 0.78]2 studies · 218 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions to reduce Staphylococcus aureus in the management of eczema
2019 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.