Topical antibiotics with steroids vs topical steroid: Withdrawals due to adverse events
It is very uncertain whether topical steroid plus topical antibiotic changes adverse events requiring withdrawal from treatment compared with topical steroid (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Topical steroid plus topical antibiotic vs topical steroid Adverse events requiring withdrawal from treatment · children and adults with eczema It is very uncertain whether topical steroid plus topical antibiotic changes adverse events requiring withdrawal from treatment compared with topical steroid (very low certainty). Interventions to reduce Staphylococcus aureus in the management of eczema (2019) · Cochrane Headline outcomes only | RR 1.24 [0.21, 7.25] | 4 studies · 325 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions to reduce Staphylococcus aureus in the management of eczema 2019 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.