Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

17 questions · 17 findings · 2 reviews

No studies found 3 · 17.6%GRADE not reported 0 · 0%Very low 13 · 76.5%Low 1 · 5.9%Moderate 0 · 0%High 0 · 0%

Topical anesthetics vs placebo or no intervention

Episodes of apnea · lumbar puncture in newborn infants

It is very uncertain whether topical anesthetics changes apnea: occurrence of one or more episodes№ of LPs: 100(1 quasi‐RCT) compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Topical ophthalmic anesthetic plus NSAID vs placebo

Proportion of participants without complete resolution of epithelial defects by 24 to 72 hours · corneal abrasion (post‐surgical)

It is very uncertain whether topical ophthalmic anesthetic plus NSAID changes proportion of participants without complete resolution of epithelial… compared with placebo (very low certainty).

1 finding from 1 review