Findings

What do systematic reviews say?

24 questions · 26 findings · 4 reviews

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No studies found 4 · 15.4%GRADE not reported 0 · 0%Very low 4 · 15.4%Low 8 · 30.8%Moderate 6 · 23.1%High 4 · 15.4%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- Topical NSAIDs vs placebo · Treatment success Fair, good or excellent effectiveness
  Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
  RR 1.49 [1.04, 2.14]
  1 study · 85 participants
  Low
Direct match · question page
- Topical NSAIDs vs placebo · Function/disability
  Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
Direct match · question page
- Topical NSAIDs vs topical placebo · Topical diclofenac gel (as Emulgel) Clinical success (eg 50% reduction in pain)
  Topical NSAIDs for acute musculoskeletal pain in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 314 participants
  High
Direct match · question page
- Topical NSAIDs vs topical placebo · Topical ibuprofen gel Clinical success (eg 50% reduction in pain)
  Topical NSAIDs for acute musculoskeletal pain in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 241 participants
  Moderate
Direct match · question page
- Topical NSAIDs vs placebo · Pain 0 to 10 visual analogue scale (0 = no pain)
  Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 153 participants
  Very low

Topical NSAIDs vs topical placebo

All topical NSAIDs Local adverse events · adults with strains, sprains, or muscle pull

1 finding from 1 review

Topical NSAIDs for acute musculoskeletal pain in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
42 studies · 6125 participants
High

Topical NSAIDs vs topical placebo

All topical NSAIDs Systemic adverse events · adults with strains, sprains, or muscle pull

1 finding from 1 review

Topical NSAIDs for acute musculoskeletal pain in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
38 studies · 5372 participants
High

Topical NSAIDs vs topical placebo

All topical NSAIDs Withdrawals ‐ adverse events · adults with strains, sprains, or muscle pull

1 finding from 1 review

Topical NSAIDs for acute musculoskeletal pain in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
42 studies · 5790 participants
High

Topical NSAIDs vs topical placebo

At least 50% reduction in pain · adults with strains, sprains, or muscle pull

2 findings from 1 review

Topical NSAIDs for acute musculoskeletal pain in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 314 participants
High
Topical NSAIDs for acute musculoskeletal pain in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 348 participants
Moderate

Topical NSAIDs vs topical placebo

Clinical success (eg 50% reduction in pain) Chronic conditions · adults with strains, sprains, or muscle pull

1 finding from 1 review

Topical NSAIDs for acute musculoskeletal pain in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 241 participants
Moderate

Topical NSAIDs vs topical placebo

Serious adverse events · adults with strains, sprains, or muscle pull

1 finding from 1 review

Topical NSAIDs for acute musculoskeletal pain in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Topical NSAIDs vs control

Reduction in pain intensity · analgesia in traumatic corneal abrasions

The review found no eligible studies for this question.

1 finding from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical NSAIDs vs control

Rescue analgesia · analgesia in traumatic corneal abrasions

Topical NSAIDs may leads to lower use of rescue oral analgesia at 24 hours compared with control (low certainty).

2 findings from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
RR 0.46 [0.34, 0.61]
4 studies · 481 participants
Low
Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical NSAIDs vs control

Proportion of abrasions healed after 24 hours · analgesia in traumatic corneal abrasions

Topical NSAIDs showed no clear difference in proportion of abrasions healed after 24 hours compared with control (low certainty).

1 finding from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
RR 1 [0.81, 1.23]
1 study · 28 participants
Low

Topical NSAIDs vs control

Proportion of abrasions healed after 48 hours · analgesia in traumatic corneal abrasions

Topical NSAIDs showed no clear difference in proportion of abrasions healed after 48 hours compared with control (low certainty).

1 finding from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
RR 1 [0.88, 1.14]
1 study · 28 participants
Low

Topical NSAIDs vs control

Complications of corneal abrasion · analgesia in traumatic corneal abrasions

It is very uncertain whether topical NSAIDs changes complications of corneal abrasion compared with control (very low certainty).

1 finding from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
RR 0.44 [0.07, 2.96]
6 studies · 609 participants
Very low

Topical NSAIDs vs control

Adverse drug events · analgesia in traumatic corneal abrasions

It is very uncertain whether topical NSAIDs changes drug‐related adverse events compared with control (very low certainty).

1 finding from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
RR 2.95 [0.32, 27.6]
2 studies · 163 participants
Very low

Topical NSAIDs vs placebo

Pain intensity (0‐10cm visual analogue scale) · Adults with lateral elbow pain

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 153 participants
Very low

Topical NSAIDs vs placebo

Treatment success Fair, good or excellent effectiveness · Adults with lateral elbow pain

Topical NSAIDs may leads to higher treatment success Fair, good or excellent effectiveness compared with placebo (low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
RR 1.49 [1.04, 2.14]
1 study · 85 participants
Low

Topical NSAIDs vs placebo

Function/disability · Adults with lateral elbow pain

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical NSAIDs vs placebo

Quality of life · Adults with lateral elbow pain

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical NSAIDs vs placebo

Withdrawals due to adverse events · Adults with lateral elbow pain

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 185 participants
Low

Topical NSAIDs vs placebo

Adverse events · Adults with lateral elbow pain

Topical NSAIDs showed no clear difference in adverse events compared with placebo (low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
RR 1.55 [0.2, 12.14]
3 studies · 153 participants
Low

Intervention not reported

Topical diclofenac gel or solution Clinical success (for example 50% reduction in pain) · adults with chronic musculoskeletal pain (osteoarthritis)

1 finding from 1 review

Topical NSAIDs for chronic musculoskeletal pain in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 2342 participants
Moderate

Intervention not reported

Topical ketoprofen gel Clinical success (for example 50% reduction in pain) · adults with chronic musculoskeletal pain (osteoarthritis)

1 finding from 1 review

Topical NSAIDs for chronic musculoskeletal pain in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 2573 participants
Moderate