What do systematic reviews say?

Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement

• Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 106 participants
  Very low

Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement

The review found no eligible studies for this question.

• Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement

The review found no eligible studies for this question.

• Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement

The review found no eligible studies for this question.

• Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement

• Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 106 participants
  Low

Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement

The review found no eligible studies for this question.

• Debridement for surgical wounds 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Negative pressure wound therapy vs standard dressing

Negative pressure wound therapy probably leads to lower surgical site infection (proportion of participants in each group… compared with standard dressing (moderate certainty).

• Negative pressure wound therapy for surgical wounds healing by primary closure 2022 · Cochrane Headline outcomes only
  RR 0.73 [0.63, 0.85]
  44 studies · 11403 participants
  Moderate

Topical antibiotics vs no topical antibiotic.

Topical antibiotics probably leads to lower surgical site infection compared with no topical antibiotic. (moderate certainty).

• Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes only
  RR 0.61 [0.42, 0.87]
  7 studies · 5427 participants
  Moderate

Topical antibiotics vs antiseptic agent

Topical antibiotics probably leads to lower surgical site infection compared with antiseptic (moderate certainty).

• Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes only
  RR 0.49 [0.3, 0.8]
  4 studies · 1299 participants
  Moderate

Preoperative showering with chlorhexidine 4% vs placebo

Preoperative showering with chlorhexidine 4% showed no clear difference in surgical site infection compared with placebo (high certainty).

• Preoperative bathing or showering with skin antiseptics to prevent surgical site infection 2015 · Cochrane Headline outcomes only
  RR 0.91 [0.8, 1.04]
  4 studies · 7791 participants
  High

4% chlorhexidine gluconate (CHG) vs soap

It is very uncertain whether chlorhexidine 4% changes surgical site infection compared with bar soap (very low certainty).

• Preoperative bathing or showering with skin antiseptics to prevent surgical site infection 2015 · Cochrane Headline outcomes only
  RR 1.02 [0.57, 1.84]
  3 studies · 1443 participants
  Very low

Chlorhexadine 4% vs no WASH intervention

It is very uncertain whether chlorhexadine 4% changes surgical site infection compared with no wash (very low certainty).

• Preoperative bathing or showering with skin antiseptics to prevent surgical site infection 2015 · Cochrane Headline outcomes only
  RR 0.82 [0.26, 2.62]
  3 studies · 1142 participants
  Very low

Early dressing removal vs delayed dressing removal

It is very uncertain whether early dressing removal changes superficial surgical site infection Superficial surgical site… compared with delayed dressing removal (very low certainty).

• Early versus delayed dressing removal after primary closure of clean and clean‐contaminated surgical wounds 2015 · Cochrane Headline outcomes only
  RR 0.64 [0.32, 1.28]
  3 studies · 280 participants
  Very low

Subcuticular sutures vs surgical tapes

It is very uncertain whether subcuticular sutures changes surgical site infection Incidence of wound infection compared with surgical tapes (very low certainty).

• Subcuticular sutures for skin closure in non‐obstetric surgery 2020 · Cochrane Headline outcomes only
  RR 1.31 [0.4, 4.27]
  6 studies · 354 participants
  Very low

Subcuticular sutures vs surgical zippers

It is very uncertain whether subcuticular sutures changes surgical site infection Incidence of wound infection compared with surgical zippers (very low certainty).

• Subcuticular sutures for skin closure in non‐obstetric surgery 2020 · Cochrane Headline outcomes only
  RR 0.8 [0.08, 8.48]
  3 studies · 424 participants
  Very low

Zinc oxide mesh vs placebo mesh

• Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal pilonidal… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 64 participants
  GRADE not reported

Lietofix cream vs iodoform dressing

• Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal pilonidal… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 205 participants
  GRADE not reported

Hydrogel dressings vs povidone‐iodine

It is very uncertain whether hydrogel dressing changes adverse effects (surgical site infection or allergic reaction) compared with wound cleaning with 10% povidone iodine (very low certainty).

• Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal pilonidal… 2022 · Cochrane Headline outcomes only
  RR 2.13 [0.22, 21.17]
  1 study · 31 participants
  Very low

Platelet‐rich plasma gel vs absorbent sterile cotton gauze

The review found no eligible studies for this question.

• Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal pilonidal… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Gentamicin‐impregnated collagen sponge vs no dressing

The review found no eligible studies for this question.

• Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal pilonidal… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found