Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

20 questions · 24 findings · 4 reviews

No studies found 6 · 25%GRADE not reported 0 · 0%Very low 6 · 25%Low 11 · 45.8%Moderate 1 · 4.2%High 0 · 0%

Short interval vs long interval

Pregnancy rate · women trying to conceive by intrauterine insemination

Short interval may leads to lower pregnancy rate per couple ‐ 24 hours versus 34 to 36 hours compared with long interval (low certainty).

3 findings from 1 review

Short interval vs long interval

Miscarriage · women trying to conceive by intrauterine insemination

It is very uncertain whether short interval changes miscarriage rate per pregnancy ‐ 24 hours versus 34 to 36 hours compared with long interval (very low certainty).

3 findings from 1 review

Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes

Catheter‐related blood stream infection · patients with a central venous catheter

Longer intervals (5‐15 days) (intervention) showed no clear difference in catheter‐related blood stream infection (CRBSI) compared with shorter intervals (2‐5 days) (control) between dressing changes (low certainty).

1 finding from 1 review

Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes

All‐cause mortality · patients with a central venous catheter

Longer intervals (5‐15 days) (intervention) showed no clear difference in all‐cause mortality compared with shorter intervals (2‐5 days) (control) between dressing changes (low certainty).

1 finding from 1 review

Longer intervals (5‐15 days) (intervention) vs shorter intervals (2‐5 days) (control) between dressing changes

Pain № of participants: 193 (2 RCTs) · patients with a central venous catheter

Longer intervals (5‐15 days) (intervention) showed no clear difference in pain № of participants: 193 (2 RCTs) compared with shorter intervals (2‐5 days) (control) between dressing changes (low certainty).

1 finding from 1 review

Two doses of HPV vaccine with longer interval vs two doses of HPV vaccine with shorter interval

High‐grade cervical, vulval, vaginal, penile, or anal intraepithelial neoplasia · 9‐ to 14‐year‐old females and males

The review found no eligible studies for this question.

1 finding from 1 review

Two doses of HPV vaccine with longer interval vs two doses of HPV vaccine with shorter interval

Serious adverse events at up to 5‐year · 9‐ to 14‐year‐old females and males

It is very uncertain whether two doses of HPV vaccine with longer interval changes serious adverse events at up to 5‐year compared with two doses of HPV vaccine with shorter interval (very low certainty).

1 finding from 1 review