Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

33 questions · 36 findings · 3 reviews · Gut · Headline outcomes only

No studies found 5 · 13.9%GRADE not reported 2 · 5.6%Very low 21 · 58.3%Low 7 · 19.4%Moderate 1 · 2.8%High 0 · 0%

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Quality of life · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

The review found no eligible studies for this question.

1 finding from 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Adverse effects ( · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes adverse effects ( compared with initiation of prophylactic therapy immediately after surgery (very low certainty).

1 finding from 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Clinical recurrence (until week 102) · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes clinical recurrence (until week 102) compared with initiation of prophylactic therapy immediately after surgery (very low certainty).

1 finding from 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Endoscopic recurrence · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes endoscopic recurrence (at week 102) compared with initiation of prophylactic therapy immediately after surgery (very low certainty).

1 finding from 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Surgical recurrence ( · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes surgical recurrence ( compared with initiation of prophylactic therapy immediately after surgery (very low certainty).

1 finding from 1 review

Intensification of prophylactic therapy guided by colonoscopy vs intensification guided by clinical recurrence

Recurrence · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

Intensification of prophylactic therapy guided by colonoscopy showed no clear difference in clinical recurrence ( compared with intensification guided by clinical recurrence (low certainty).

1 finding from 1 review

Intensification of prophylactic therapy guided by colonoscopy vs intensification guided by clinical recurrence

Endoscopic recurrence · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

Intensification of prophylactic therapy guided by colonoscopy may leads to lower endoscopic recurrence ( compared with intensification guided by clinical recurrence (low certainty).

1 finding from 1 review

Intensification of prophylactic therapy guided by colonoscopy vs intensification guided by clinical recurrence

Adverse effects ( · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether intensification of prophylactic therapy guided by colonoscopy changes adverse effects ( compared with intensification guided by clinical recurrence (very low certainty).

1 finding from 1 review

Drain use vs No drain

All‐cause mortality · people undergoing elective pancreatic resections

Drain use showed no clear difference in mortality compared with no drain use following pancreatic surgery (low certainty).

2 findings from 1 review

Active drain vs passive drain

Intra‐abdominal infection · people undergoing elective pancreatic resections

It is very uncertain whether active drain changes intra‐abdominal infection compared with passive drain following pancreatic surgery (very low certainty).

1 finding from 1 review

Active drain vs passive drain

Length of hospital stay · people undergoing elective pancreatic resections

It is very uncertain whether active drain changes length of hospital stay compared with passive drain following pancreatic surgery (very low certainty).

1 finding from 1 review

Early vs late drain removal following pancreatic surgery

All‐cause mortality · people undergoing elective pancreatic resections

It is very uncertain whether early changes mortality compared with late drain removal following pancreatic surgery (very low certainty).

2 findings from 1 review