Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

317 questions · 322 findings · 62 reviews · Eyes and Vision · Headline outcomes only

No studies found 94 · 29.2%GRADE not reported 15 · 4.7%Very low 63 · 19.6%Low 91 · 28.3%Moderate 45 · 14%High 14 · 4.3%

Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention

Change in visual loss associated with PSR: visual loss is defined by the deterioration of visual acuity of 3 lines or more with the Snellen chart · type 1 or type 2 diabetics

It is very uncertain whether blood pressure intervention/intensive blood pressure intervention changes visual acuity (loss of 3 lines or more) by 5 years compared with placebo/standard blood pressure intervention (very low certainty).

1 finding from 1 review

Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention

Adverse events: hypotension · type 1 or type 2 diabetics

Blood pressure intervention/intensive blood pressure intervention may leads to higher adverse events—hypotension compared with placebo/standard blood pressure intervention (low certainty).

1 finding from 1 review

LipiFlow vs basic warm compresses

Mean change from baseline in meibomian gland expression scores at 1 to 4 weeks (higher is favored) · people with dry eye

It is very uncertain whether lipiFlow changes mean change from baseline in meibomian gland expression scores at 1… compared with basic warm compresses (very low certainty).

1 finding from 1 review

Low‐ vs high‐energy diode trans‐scleral cyclophotocoagulation

Control of intraocular pressure · people with primary open‐angle glaucoma and no previous glaucoma surgery

Low‐ showed no clear difference in control of intraocular pressure compared with high‐energy diode trans‐scleral cyclophotocoagulation (low certainty).

1 finding from 1 review