Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,721 questions · 19,640 findings · 2,039 reviews · Headline outcomes only

No studies found 3,754 · 19.1%GRADE not reported 1,273 · 6.5%Very low 4,859 · 24.7%Low 5,568 · 28.4%Moderate 3,240 · 16.5%High 946 · 4.8%

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Prehabilitation vs no prehabilitation

Functional capacity · Patients with outcomes after colorectal cancer surgery
3 findings from 1 review

Antidepressant plus antipsychotic vs placebo plus antidepressant

Clinical response of depression · adults with psychotic depression

It is very uncertain whether antidepressant plus antipsychotic changes clinical response of depression compared with placebo plus antidepressant (very low certainty).

2 findings from 1 review

Antidepressant plus antipsychotic vs placebo plus antidepressant

Change in depression severity from baseline · adults with psychotic depression

The review found no eligible studies for this question.

2 findings from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Pre‐eclampsia · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in pre‐Eclampsia compared with c‐IVF (moderate certainty).

1 finding from 1 review

Probiotics vs placebo

Hypertensive disorders of pregnancy: pre‐eclampsia · preventing gestational diabetes

Probiotics leads to higher hypertensive disorders of pregnancy (pre‐eclampsia) compared with placebo (high certainty).

1 finding from 1 review

Antidepressants vs placebo

Clinical response of depression · adults with psychotic depression

It is very uncertain whether antidepressant changes clinical response of depression compared with placebo (very low certainty).

1 finding from 1 review

Prevention of eclampsia: short vs standard maintenance regimen (subgroups by type of short regimen)

Side effect: respiratory depression · women with pre‐eclampsia

Prevention of eclampsia: short showed no clear difference in side effect: respiratory depression compared with standard maintenance regimen (subgroups by type of short regimen) (low certainty).

1 finding from 1 review