Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 17 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 7 · 41.2%Low 4 · 23.5%Moderate 4 · 23.5%High 2 · 11.8%

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment · management of opium withdrawal

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: baclofen versus clonidine compared with other pharmacological detoxification treatment (very low certainty).

4 findings from 1 review
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Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment: clonidine versus clonidine plus amantadine, inpatient setting · management of opium withdrawal

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus clonidine plus amantadine,… compared with other pharmacological detoxification treatment (very low certainty).

1 finding from 1 review

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment: clonidine versus buprenorphine, inpatient setting · management of opium withdrawal

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus buprenorphine, inpatient… compared with other pharmacological detoxification treatment (very low certainty).

1 finding from 1 review

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment: methadone versus methadone plus gabapentin · management of opium withdrawal

Pharmacological detoxification treatment showed no clear difference in completion of treatment: methadone versus methadone plus gabapentin compared with other pharmacological detoxification treatment (low certainty).

1 finding from 1 review

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Withdrawal symptoms · management of opium withdrawal
4 findings from 1 review
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Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to

use of opiate during treatment ( · patients with opioid detoxification

Any Psychosocial plus any Pharmacological probably leads to lower use of opiate during the treatment objective compared with any Pharmachological alone compared to (moderate certainty).

1 finding from 1 review

Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to

Dropout · patients with opioid detoxification

Any Psychosocial plus any Pharmacological probably leads to lower dropouts ‐ All studies objective compared with any Pharmachological alone compared to (moderate certainty).

1 finding from 1 review

Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to

Dropout ‐ Studies with low risk of bias · patients with opioid detoxification

Any Psychosocial plus any Pharmacological leads to lower dropouts ‐ Only studies with low risk of bias objeive compared with any Pharmachological alone compared to (high certainty).

1 finding from 1 review

Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to

Results at · patients with opioid detoxification

Any Psychosocial plus any Pharmacological probably leads to lower results at compared with any Pharmachological alone compared to (moderate certainty).

2 findings from 1 review

Any Psychosocial plus any Pharmacological vs any Pharmachological alone compared to

Compliance as clinical absences during the tratment objective · patients with opioid detoxification

Any Psychosocial plus any Pharmacological probably leads to lower compliance as clinical absences during the tratment objective compared with any Pharmachological alone compared to (moderate certainty).

1 finding from 1 review