acceptability ‐ drop‐outs due to adverse events: post‐intervention · adults with long‐term physical conditions (18 years or older)
It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to adverse events: post‐intervention compared with placebo (very low certainty).
1 finding from 1 review
Acceptability · adults with long‐term physical conditions (18 years or older)
It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to any cause: post‐intervention compared with placebo (very low certainty).
2 findings from 1 review
Incidence of depression ‐ post‐intervention: 0 months · adults with long‐term physical conditions (18 years or older)
It is very uncertain whether pharmacological interventions changes incidence of depression ‐ post‐intervention: 0 months compared with placebo (very low certainty).
1 finding from 1 review
Incidence of depression ‐ short‐term: < 6 months · adults with long‐term physical conditions (18 years or older)
It is very uncertain whether pharmacological interventions changes incidence of depression ‐ short‐term: < 6 months compared with placebo (very low certainty).
1 finding from 1 review
Incidence of depression ‐ medium term: 6‐12 months · adults with long‐term physical conditions (18 years or older)
It is very uncertain whether pharmacological interventions changes incidence of depression ‐ medium‐term: 6‐12 months compared with placebo (very low certainty).
1 finding from 1 review
Incidence of depression ‐ long‐term: >12 months · adults with long‐term physical conditions (18 years or older)
1 finding from 1 review
Tolerability ‐ total number of adverse events · adults with long‐term physical conditions (18 years or older)
1 finding from 1 review
Repetition of SH at post‐intervention · self‐harm in adults
It is very uncertain whether newer generation antidepressants (NGAs) changes repetition of SH by post‐intervention (NGA class)№ of participants:… compared with placebo (very low certainty).
3 findings from 1 review
OR 0.59 [0.29, 1.19]
Studies not reported
Very low
OR 0.67 [0.18, 2.41]
Studies not reported
Very low
OR 0.55 [0.24, 1.29]
Studies not reported
Low
Repetition of SH at post‐intervention · self‐harm in adults
Antipsychotics may leads to lower repetition of SH by post‐intervention№ of participants: 30(1 RCT) compared with placebo (low certainty).
1 finding from 1 review
OR 0.09 [0.02, 0.5]
Studies not reported
Low
Repetition of SH at post‐intervention · self‐harm in adults
Antipsychotics showed no clear difference in repetition of SH by post‐intervention№ of participants: 53(1 RCT) compared with another comparator drug or dose (low certainty).
1 finding from 1 review
OR 1.51 [0.5, 4.58]
Studies not reported
Low
Repetition of SH at post‐intervention · self‐harm in adults
It is very uncertain whether mood stabilisers, including antiepileptics and lithium changes repetition of SH by post‐intervention№ of participants: 167(1 RCT) compared with placebo (very low certainty).
1 finding from 1 review
OR 0.99 [0.33, 2.95]
Studies not reported
Very low
Repetition of SH at post‐intervention · self‐harm in adults
Natural products showed no clear difference in repetition of SH by post‐intervention№ of participants: 49(1 RCT) compared with placebo (low certainty).
1 finding from 1 review
OR 1.33 [0.38, 4.62]
Studies not reported
Low
Depression response (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months
It is very uncertain whether antidepressants changes depression response (acute phase, 5 ≤ 12 weeks) compared with any other pharmacological intervention (very low certainty).
1 finding from 1 review
RR 0.98 [0.76, 1.27]
Studies not reported
Very low
Depression remission · women of any age, with PND up to 12 months
It is very uncertain whether antidepressants changes depression remission (acute phase, 5 ≤ 12 weeks) compared with any other pharmacological intervention (very low certainty).
2 findings from 1 review
RR 0.98 [0.68, 1.41]
Studies not reported
Very low
no estimate extracted
Studies not reported
Low
Adverse events · women of any age, with PND up to 12 months
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Depression response (early phase, < 5 weeks) · women of any age, with PND up to 12 months
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Depression severity (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Acceptability ‐ total dropouts · women of any age, with PND up to 12 months
It is very uncertain whether antidepressants changes treatment acceptability ‐dropouts compared with any other pharmacological intervention (very low certainty).
1 finding from 1 review
RR 1.74 [0.99, 3.06]
Studies not reported
Very low
Child‐related outcomes · women of any age, with PND up to 12 months
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Severity of PTSD symptoms ‐ Clinician‐rated · adults experiencing acute traumatic stress symptoms
1 finding from 1 review