What do systematic reviews say?

Perioperative antibiotics vs placebo or no antibiotic

The review found no eligible studies for this question.

• Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Perioperative antibiotics vs placebo or no antibiotic

It is very uncertain whether perioperative antibiotics changes wound infection Proportion of wound infections compared with placebo or no antibiotic (very low certainty).

• Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery 2019 · Cochrane Headline outcomes only
  RR 0.11 [0.01, 1.95]
  1 study · 44 participants
  Very low

Perioperative antibiotics vs placebo or no antibiotic

The review found no eligible studies for this question.

• Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Perioperative antibiotics vs placebo or no antibiotic

The review found no eligible studies for this question.

• Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Perioperative antibiotics vs placebo or no antibiotic

The review found no eligible studies for this question.

• Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Antibiotics vs no antibiotics

It is very uncertain whether antibiotics changes surgical site infections* Time frame: 2 to 6 weeks compared with no antibiotics (very low certainty).

• Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
  RR 0.42 [0.21, 0.85]
  5 studies · 226 participants
  Very low

Antibiotics vs no antibiotics

It is very uncertain whether antibiotics changes death (any case) Time frame: 2 to 4 weeks compared with no antibiotics (very low certainty).

• Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
  RR 0.27 [0.02, 3.69]
  2 studies · 87 participants
  Very low

Antibiotics vs no antibiotics

It is very uncertain whether antibiotics changes graft loss (including death with functioning graft) Time frame: 2… compared with no antibiotics (very low certainty).

• Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
  RR 2.89 [0.12, 67.96]
  1 study · 53 participants
  Very low

Antibiotics vs no antibiotics

It is very uncertain whether antibiotics changes other infection: UTI Time frame: 2 to 6 weeks compared with no antibiotics (very low certainty).

• Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
  RR 0.88 [0.68, 1.14]
  3 studies · 150 participants
  Very low

Antibiotics vs no antibiotics

It is very uncertain whether antibiotics changes other infection: septicaemia Time frame: 2 to 6 weeks compared with no antibiotics (very low certainty).

• Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
  RR 0.5 [0.11, 2.19]
  2 studies · 90 participants
  Very low

Antibiotics vs no antibiotics

It is very uncertain whether antibiotics changes other infection: pneumonia Time frame: up to 6 weeks compared with no antibiotics (very low certainty).

• Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
  RR 0.53 [0.21, 1.32]
  1 study · 37 participants
  Very low

Antibiotics vs no antibiotics

The review found no eligible studies for this question.

• Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

• Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery 2017 · Cochrane Headline outcomes only
  no estimate extracted
  644 participants
  Very low

Extended vs short duration antibiotics

It is very uncertain whether extended changes surgical site infections: liver transplant recipients Time frame: 30… compared with short duration antibiotics (very low certainty).

• Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
  RR 1.31 [0.61, 2.81]
  1 study · 97 participants
  Very low

Extended vs short duration antibiotics

It is very uncertain whether extended changes death (any cause) Time frame: 30 days compared with short duration antibiotics (very low certainty).

• Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
  RR 0.2 [0.01, 3.98]
  1 study · 97 participants
  Very low

Extended vs short duration antibiotics

It is very uncertain whether extended changes graft loss (including death with functioning graft) Time frame: 30… compared with short duration antibiotics (very low certainty).

• Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
  RR 0.99 [0.49, 2]
  2 studies · 302 participants
  Very low

Extended vs short duration antibiotics

It is very uncertain whether extended changes other infection: UTI Time frame: 30 days compared with short duration antibiotics (very low certainty).

• Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
  RR 0.49 [0.13, 1.85]
  1 study · 97 participants
  Very low

Extended vs short duration antibiotics

It is very uncertain whether extended changes other infection: septicaemia Time frame: 30 days compared with short duration antibiotics (very low certainty).

• Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
  RR 0.9 [0.51, 1.58]
  2 studies · 302 participants
  Very low

Extended vs short duration antibiotics

It is very uncertain whether extended changes other infection: pneumonia Time frame: 30 days compared with short duration antibiotics (very low certainty).

• Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
  RR 10.78 [0.61, 189.77]
  1 study · 97 participants
  Very low

Extended vs short duration antibiotics

The review found no eligible studies for this question.

• Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found