Parathyroidectomy probably leads to lower cure of PHPT compared with observation (moderate certainty).
Parathyroidectomy showed no clear difference in hospitalisation for hypercalcaemia, renal impairment or pancreatitis compared with observation (low certainty).
It is very uncertain whether minimally invasive parathyroidectomy changes success rate (eucalcaemia) (a) compared with bilateral neck exploration (very low certainty).
Minimally invasive parathyroidectomy may leads to lower total incidence of perioperative adverse events (number) compared with bilateral neck exploration (low certainty).
The review found no eligible studies for this question.
The intervention leads to lower parathyroidectomy (9 months) (high certainty).
Meta-analysis of randomised trials of vitamin D supplementation for Parathyroidectomy: RR 0.82 (95% CI 0.05 to 12.47), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
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