Cochrane · systematic review · CD010787
Minimally invasive parathyroidectomy guided by intraoperative parathyroid hormone monitoring (IOPTH) and preoperative imaging versus bilateral neck exploration for primary hyperparathyroidism in adults
Ahmadieh, H, Kreidieh, O, Akl, EA, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
Metabolic and Endocrine DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 5 · 71.4%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Minimally invasive parathyroidectomy versus bilateral neck exploration for primary hyperparathyroidism in adults
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Success rate (eucalcaemia) (a) Minimally invasive parathyroidectomy vs bilateral neck exploration | RR 0.98 [0.94, 1.03] | 5 studies · 266 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Total incidence of perioperative adverse events (number) Minimally invasive parathyroidectomy vs bilateral neck exploration | RR 0.5 [0.33, 0.76] | 5 studies · 236 participants | Low Downgraded: risk of bias, imprecision |
All‐cause mortality Minimally invasive parathyroidectomy vs bilateral neck exploration | no estimate extracted | NR | Very low Downgraded: imprecision |
Health‐related quality of life Minimally invasive parathyroidectomy vs bilateral neck exploration | no estimate extracted | NR | Very low Downgraded: imprecision |
Cosmetic satisfaction Minimally invasive parathyroidectomy vs bilateral neck exploration | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision, indirectness |
Duration of surgery (time from skin incision to skin closure) Minimally invasive parathyroidectomy vs bilateral neck exploration | no estimate extracted | 3 studies · 171 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Length of hospital stay Minimally invasive parathyroidectomy vs bilateral neck exploration | no estimate extracted | NR | No studies |