Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

25 questions · 26 findings · 3 reviews · Pregnancy and Childbirth

No studies found 11 · 42.3%GRADE not reported 1 · 3.8%Very low 8 · 30.8%Low 6 · 23.1%Moderate 0 · 0%High 0 · 0%

Paracetamol vs placebo

Relief of pain · women who have given birth vaginally, requiring analgesia for after‐birth pains.

It is very uncertain whether paracetamol changes adequate pain relief as reported by the woman (6 hours) compared with placebo (very low certainty).

1 finding from 1 review

Paracetamol vs placebo

Need for additional pain relief (up to 4 hours) · women who have given birth vaginally, requiring analgesia for after‐birth pains.

It is very uncertain whether paracetamol changes need for additional pain relief (up to 4 hours) compared with placebo (very low certainty).

1 finding from 1 review

Paracetamol vs placebo

Maternal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.

It is very uncertain whether paracetamol changes maternal adverse events (up to 4 hours and at 6 hours) compared with placebo (very low certainty).

1 finding from 1 review

Paracetamol vs NSAIDs

Relief of pain · women who have given birth vaginally, requiring analgesia for after‐birth pains.

It is very uncertain whether paracetamol changes adequate pain relief as reported by the woman (6 hours) compared with NSAID (very low certainty).

1 finding from 1 review

Paracetamol vs NSAIDs

Maternal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.

It is very uncertain whether paracetamol changes maternal adverse events (up to 4 hours and at 6 hours) compared with NSAID (very low certainty).

1 finding from 1 review

Paracetamol (single administration, any dose) vs placebo

Adequate pain relief as reported by women · women with perineal pain following childbirth

Paracetamol (single administration, any dose) may leads to higher adequate pain relief as reported by women compared with placebo (low certainty).

1 finding from 1 review

Paracetamol (single administration, any dose) vs placebo

Maternal drug adverse effects (sleepiness) · women with perineal pain following childbirth

Paracetamol (single administration, any dose) showed no clear difference in maternal drug adverse effects (sleepiness) compared with placebo (low certainty).

1 finding from 1 review

NSAID (single administration, any dose) vs paracetamol

Need for additional analgesia (4 hours after administration) · women with perineal pain in the early postpartum period

It is very uncertain whether NSAID (single administration, any dose) changes need for additional analgesia (4 hours after administration) compared with paracetamol (very low certainty).

1 finding from 1 review