Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

56 questions · 56 findings · 13 reviews · Emergency and Critical Care · Headline outcomes only

No studies found 11 · 19.6%GRADE not reported 6 · 10.7%Very low 7 · 12.5%Low 15 · 26.8%Moderate 9 · 16.1%High 8 · 14.3%

Fibrinogen concentrate vs any comparator

Thrombotic episodes (arterial and venous graft occlusion, pulmonary embolus, deep venous thrombosis) Proportion with event · bleeding patients or at risk of severe bleeding

It is very uncertain whether fibrinogen concentrate changes thrombotic episodes (arterial and venous graft occlusion, pulmonary… compared with any comparator (very low certainty).

1 finding from 1 review

Intervention not reported

Good neurological outcome · adults after cardiopulmonary resuscitation

The intervention may leads to higher good neurological outcome (low certainty).

1 finding from 1 review

Intervention not reported

Survival · adults after cardiopulmonary resuscitation

The intervention showed no clear difference in survival (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events – pneumonia · adults after cardiopulmonary resuscitation

The intervention showed no clear difference in adverse events – pneumonia (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events – hypokalaemia · adults after cardiopulmonary resuscitation

It is very uncertain whether the intervention changes adverse events – hypokalaemia (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse events – arrhythmia · adults after cardiopulmonary resuscitation

The intervention may leads to higher adverse events – arrhythmia (low certainty).

1 finding from 1 review

Enteral vs parenteral nutrition

All‐cause mortality · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

Enteral showed no clear difference in mortality compared with parenteral nutrition (low certainty).

1 finding from 1 review