Fibrinogen concentrate vs any comparator: Thrombotic episodes (arterial and venous graft occlusion, pulmonary embolus, deep venous thrombosis) Proportion with event
It is very uncertain whether fibrinogen concentrate changes thrombotic episodes (arterial and venous graft occlusion, pulmonary… compared with any comparator (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Fibrinogen concentrate vs any comparator Thrombotic episodes (arterial and venous graft occlusion, pulmonary embolus, deep venous thrombosis) Proportion with event · bleeding patients or at risk of severe bleeding It is very uncertain whether fibrinogen concentrate changes thrombotic episodes (arterial and venous graft occlusion, pulmonary… compared with any comparator (very low certainty). Fibrinogen concentrate in bleeding patients (2013) · Cochrane Headline outcomes only | RR 1.03 [0.27, 3.97] | 3 studies · 124 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Fibrinogen concentrate in bleeding patients 2013 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.