Preimplantation complications · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
Hyperbaric oxygen (HBO) therapy led to lower preimplantation complications compared with no HBO therapy; GRADE not reported.
1 finding from 1 review
Analysis 1.1 (Dichotomous outcomes: Preimplantation complications): Risk Ratio (M-H, Fixed, 95% CI), totals not selected; not estimable (no events in either arm).
1 study · 24 participants
GRADE not reported
Prosthetic failure (2 years) · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
It is very uncertain whether hyperbaric oxygen (HBO) therapy changes prosthetic failure compared with no HBO therapy (very low certainty).
1 finding from 1 review
Marginal bone level change · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
1 finding from 1 review
Overall denture satisfaction (0-10 scale) · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
Hyperbaric oxygen (HBO) therapy showed no clear difference in patient satisfaction (overall denture satisfaction) compared with no HBO therapy; GRADE not reported.
1 finding from 1 review
Analysis 1.2 (Overall denture satisfaction): Mean Difference (IV, Fixed, 95% CI), totals not selected (value not displayed).
1 study · 17 participants
GRADE not reported
Cost‐effectiveness · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
The review found no eligible studies for this question.
1 finding from 1 review
Implant failure · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
Hyperbaric oxygen (HBO) therapy showed no clear difference in implant failure compared with no HBO therapy; GRADE not reported.
1 finding from 1 review
Postimplantation complications · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
Hyperbaric oxygen (HBO) therapy showed no clear difference in postimplantation complications compared with no HBO therapy; GRADE not reported.
1 finding from 1 review
Behaviour · Children and adolescents (0 to 16 years) needing dental treatment
It is very uncertain whether nitrous oxide/oxygen changes behaviour (Houpt/behavioural score) compared with placebo (including no intervention) (very low certainty).
1 finding from 1 review
Dry mouth (xerostomia) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
Oxygenated glycerol triester (OGT) spray led to higher xerostomia (mouth dryness scale) compared with saliveeze (aqueous electrolyte) spray; GRADE not reported.
1 finding from 1 review
SMD 0.77 [0.38, 1.15]
2 studies
GRADE not reported
Oral health · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
1 finding from 1 review
Patient satisfaction · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
Oxygenated glycerol triester (OGT) spray showed no clear difference in patient satisfaction compared with saliveeze (aqueous electrolyte) spray; GRADE not reported.
1 finding from 1 review
Tooth survival · People with avulsed and replanted permanent (front) teeth
It is very uncertain whether hyperbaric oxygen (following replantation) changes tooth survival at 12 months compared with control (very low certainty).
1 finding from 1 review
Adverse effects · People with avulsed and replanted permanent (front) teeth
1 finding from 1 review
Pulpal healing at 12 months · People with avulsed and replanted permanent (front) teeth
It is very uncertain whether hyperbaric oxygen (following replantation) changes pulpal healing at 12 months compared with control (very low certainty).
1 finding from 1 review
Periodontal healing at 12 months · People with avulsed and replanted permanent (front) teeth
It is very uncertain whether hyperbaric oxygen (following replantation) changes periodontal healing at 12 months compared with control (very low certainty).
1 finding from 1 review
Volatile sulphur compounds (VSC), halimeter · Adults over 18 years with a clinical or self-assessed diagnosis of halitosis, without significant comorbidity (e.g. diabetes) or…
1 finding from 1 review
Borden 2002: mean change in halimeter-assessed VSC (ppb). Oxygene: -47.63 at 2 weeks (64.97% reduction), -53.28 at 4 weeks (72.67% reduction); Placebo: -39.86 at 2 weeks, -36.77 at 4 weeks (41.75%). No between-group…
1 study
GRADE not reported
Organoleptic assessment of halitosis (mean change from baseline) · Adults over 18 years with a clinical or self-assessed diagnosis of halitosis, without significant comorbidity (e.g. diabetes) or…
1 finding from 1 review
Borden 2002: mean change in organoleptic score (scale 0 to 5). Oxygene (chlorine dioxide + zinc): 0 at 2 weeks, 0.06 at 4 weeks; Placebo: 0.23 at 2 weeks, 0.16 at 4 weeks. Oxygene did not appear to reduce organoleptic…
1 study
GRADE not reported
Incidence of ORN · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
It is very uncertain whether hyperbaric oxygen therapy (HBO) following extractions changes incidence of ORN compared with perioperative antibiotic prophylaxis (penicillin G) following… (very low certainty).
1 finding from 1 review
Adverse effects · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
1 finding from 1 review
Adverse effects were an outcome of interest in the study conducting this comparison, however no mention was made of the presence or absence of any adverse events
1 study · 74 participants
Very low
Healing of MRONJ · People with established (manifest) MRONJ
It is very uncertain whether hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy changes healing of MRONJ compared with conventional therapy (very low certainty).
1 finding from 1 review