Question · asked by 1 review
Chlorine dioxide + zinc mouthwash vs placebo: Volatile sulphur compounds (VSC), halimeter
- Population
- Adults over 18 years with a clinical or self-assessed diagnosis of halitosis, without significant comorbidity (e.g. diabetes) or refractory/severe chronic periodontal disease
- Intervention
- Chlorine dioxide + zinc mouthwash
- Comparison
- placebo
- Outcome
- Volatile sulphur compounds (VSC), halimeter
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Chlorine dioxide + zinc mouthrinse (Oxygene) vs Placebo Halimeter-assessed volatile sulphur compounds (VSC) (mean change from baseline) · Adults over 18 years with a clinical or self-assessed diagnosis of halitosis, without significant comorbidity (e.g.… · 4 weeks Mouthrinses for the treatment of halitosis (2008) · Cochrane All outcomes | Borden 2002: mean change in halimeter-assessed VSC (ppb). Oxygene: -47.63 at 2 weeks (64.97% reduction), -53.28 at 4 weeks (72.67% reduction); Placebo: -39.86 at 2 weeks, -36.77 at 4 weeks (41.75%). No between-group… | 1 study | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Mouthrinses for the treatment of halitosis 2008 · Cochrane All outcomes | 2008-08 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Chlorine dioxide + zinc mouthwash vs Placebo mouthwash · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of… · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.