Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

158 questions · 175 findings · 31 reviews · Headline outcomes only

No studies found 41 · 23.4%GRADE not reported 0 · 0%Very low 48 · 27.4%Low 63 · 36%Moderate 20 · 11.4%High 3 · 1.7%

Morphine vs diamorphine

Neurodevelopmental outcomes · neonates with mechanical ventilation

The review found no eligible studies for this question.

3 findings from 1 review

IA morphine vs IM morphine

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients undergoing knee arthroscopy
3 findings from 1 review

Morphine vs placebo

Any pain‐related outcome (moderate pain improvement) · adults with neuropathic pain

It is very uncertain whether morphine changes any pain‐related outcome (moderate pain improvement) compared with placebo (very low certainty).

1 finding from 1 review

Morphine vs placebo

Withdrawal (all‐cause) · adults with neuropathic pain

It is very uncertain whether morphine changes all‐cause withdrawal compared with placebo (very low certainty).

1 finding from 1 review

Morphine vs placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients undergoing knee arthroscopy
3 findings from 1 review

Morphine vs NSAIDs

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients undergoing knee arthroscopy
3 findings from 1 review