Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

20 questions · 20 findings · 7 reviews · Effective Practice and Organisation of Care · Headline outcomes only

No studies found 2 · 10%GRADE not reported 0 · 0%Very low 7 · 35%Low 3 · 15%Moderate 7 · 35%High 1 · 5%

Summary of findings for the main comparison: comprehensive care programmes vs usual care

Parent health, functioning, and quality of life Patient‐Reported Outcomes Measurement Information System (PROMIS) (higher scores = more of the outcome of interest, which can mean improvement or deterioration depending on the outcome) · children with medical complexity
1 finding from 1 review

Pharmaceutical care vs usual care

The proportion of patients with one or more potentially inappropriate medication (PIM) · older people receiving polypharmacy

It is very uncertain whether pharmaceutical care changes the proportion of patients with one or more potentially… compared with usual care (very low certainty).

1 finding from 1 review

Pharmaceutical care vs usual care

The proportion of patients with one or more potential prescribing omission (PPO) · older people receiving polypharmacy

It is very uncertain whether pharmaceutical care changes the proportion of patients with one or more potential prescribing… compared with usual care (very low certainty).

1 finding from 1 review

Less intensive vs more intensive follow‐up after primary cancer treatment

Depression · adult cancer survivors from the following cancer sites: breast, colorectal, head‐and‐neck, Hodgkin lymphoma, melanoma, non‐small cell lung…

The review found no eligible studies for this question.

1 finding from 1 review

Less intensive vs more intensive follow‐up after primary cancer treatment

Overall survival · adult cancer survivors from the following cancer sites: breast, colorectal, head‐and‐neck, Hodgkin lymphoma, melanoma, non‐small cell lung…

Less intensive showed no clear difference in overall survival compared with more intensive follow‐up after primary cancer treatment (low certainty).

1 finding from 1 review

Less intensive vs more intensive follow‐up after primary cancer treatment

Time to detection of recurrence · adult cancer survivors from the following cancer sites: breast, colorectal, head‐and‐neck, Hodgkin lymphoma, melanoma, non‐small cell lung…

Less intensive probably leads to lower time to detection of recurrence compared with more intensive follow‐up after primary cancer treatment (moderate certainty).

1 finding from 1 review