Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

316 questions · 328 findings · 26 reviews · Oral Health

No studies found 97 · 29.6%GRADE not reported 148 · 45.1%Very low 60 · 18.3%Low 20 · 6.1%Moderate 3 · 0.9%High 0 · 0%

Oral paracetamol vs placebo

Patients with one or more adverse events · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…

Paracetamol (single oral dose, any dose or formulation; subgroups up… showed no clear difference in patients with one or more adverse events compared with placebo; GRADE not reported.

1 finding from 1 review

Single-visit root canal treatment vs Multiple-visit root canal treatment (two or more visits)

Pain at 12 months or more (long-term postobturation pain) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
1 finding from 1 review

Oral paracetamol vs placebo

At least 50% reduction in pain · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…

Paracetamol (single oral dose, any dose or formulation; subgroups up… led to higher achieving at least 50% pain relief at 4 hours (using pain intensity… compared with placebo; GRADE not reported.

3 findings from 1 review

Oral paracetamol vs placebo

Participant‐reported pain relief of 50% or greater · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…

Paracetamol (single oral dose, any dose or formulation; subgroups up… led to higher achieving at least 50% pain relief at 6 hours (using pain relief… compared with placebo; GRADE not reported.

1 finding from 1 review

Endodontic therapy (surgical or non-surgical) performed with the aid of one or more magnification devices (surgical microscope, endoscope or magnifying loupes) vs The same endodontic therapy performed without magnification devices (without visual enhancers)

Quality of root-end filling (retrograde/surgical treatment) · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment

The review found no eligible studies for this question.

1 finding from 1 review
  • Magnification devices for endodontic therapy 2015 · Cochrane All outcomes
    No included study assessed this outcome; the review notes that such secondary outcomes were only sporadically reported and were never statistically assessed.
    Studies not reported
    No studies found

Endodontic therapy (surgical or non-surgical) performed with the aid of one or more magnification devices (surgical microscope, endoscope or magnifying loupes) vs The same endodontic therapy performed without magnification devices (without visual enhancers)

Removal of broken (fractured) instruments from the root canal · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment

The review found no eligible studies for this question.

1 finding from 1 review
  • Magnification devices for endodontic therapy 2015 · Cochrane All outcomes
    No included study assessed this outcome; the review notes that such secondary outcomes were only sporadically reported and were never statistically assessed.
    Studies not reported
    No studies found

Endodontic therapy (surgical or non-surgical) performed with the aid of one or more magnification devices (surgical microscope, endoscope or magnifying loupes) vs The same endodontic therapy performed without magnification devices (without visual enhancers)

Total time required to complete the clinical procedure · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment

The review found no eligible studies for this question.

1 finding from 1 review
  • Magnification devices for endodontic therapy 2015 · Cochrane All outcomes
    No included study assessed procedure time; such outcomes were only sporadically reported and were never statistically assessed.
    Studies not reported
    No studies found

Endodontic therapy (surgical or non-surgical) performed with the aid of one or more magnification devices (surgical microscope, endoscope or magnifying loupes) vs The same endodontic therapy performed without magnification devices (without visual enhancers)

Repair of root perforations · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment

The review found no eligible studies for this question.

1 finding from 1 review
  • Magnification devices for endodontic therapy 2015 · Cochrane All outcomes
    No included study assessed this outcome; the review notes that such secondary outcomes were only sporadically reported and were never statistically assessed.
    Studies not reported
    No studies found

Endodontic therapy (surgical or non-surgical) performed with the aid of one or more magnification devices (surgical microscope, endoscope or magnifying loupes) vs The same endodontic therapy performed without magnification devices (without visual enhancers)

Quality of visualisation of root canal anatomy and morphology · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment

The review found no eligible studies for this question.

1 finding from 1 review
  • Magnification devices for endodontic therapy 2015 · Cochrane All outcomes
    No included study assessed this outcome; the review notes that such secondary outcomes were only sporadically reported and were never statistically assessed.
    Studies not reported
    No studies found

Endodontic therapy (surgical or non-surgical) performed with the aid of one or more magnification devices (surgical microscope, endoscope or magnifying loupes) vs The same endodontic therapy performed without magnification devices (without visual enhancers)

Overall success (composite of clinical and radiographic success) · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment

The review found no eligible studies for this question.

1 finding from 1 review
  • Magnification devices for endodontic therapy 2015 · Cochrane All outcomes
    >=1 year after treatment
    None of the studies fulfilled our inclusion criteria and therefore no data analysis was conducted (three potentially eligible trials were identified from 1234 records; all were excluded).
    Studies not reported
    No studies found

High-volume evacuation (HVE) vs No HVE

Reduction in level of contamination in aerosols (CFU) at more than 1 foot from oral cavity (CCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

High-volume evacuation (HVE) led to lower reduction in level of contamination in aerosols (CFU) at more than 1… compared with no HVE; GRADE not reported.

1 finding from 1 review

High-volume evacuation (HVE) vs No HVE

Reduction in level of contamination in aerosols (CFU) during ultrasonic scaling and air polishing at more than 1 foot from oral cavity (RCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether high-volume evacuation (HVE) changes reduction in level of contamination in aerosols (CFU) during… compared with no HVE (very low certainty).

1 finding from 1 review

12,500 ppm F (NaF/olaflur/dectaflur) amine fluoride gel vs Placebo gel

Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

The review found no eligible studies for this question.

1 finding from 1 review

Patient-used 5000 ppm F toothpaste, daily vs 1450 to 1500 ppm F toothpaste

Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

The review found no eligible studies for this question.

1 finding from 1 review

1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily vs 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily

Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

The review found no eligible studies for this question.

1 finding from 1 review

Slow-release fluoride device (fluoride glass beads) vs Fluoride mouthrinse

Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

The review found no eligible studies for this question.

1 finding from 1 review

Fluoride varnish vs Non-fluoride (placebo) varnish

Number of participants with more severe DLs (score 3 or 4 versus 1 or 2) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

Professionally-applied fluoride varnish (7700 ppm F ammonium… may leads to lower number of participants with more severe DLs (score 3 or 4 versus 1… compared with non-fluoride (placebo) varnish (low certainty).

1 finding from 1 review

Resin-modified glass ionomer cement for bonding orthodontic brackets vs Composite resin for bonding brackets

Number of participants with more severe DLs of aesthetic concern · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

Resin-modified glass ionomer cement for bonding orthodontic brackets showed no clear difference in number of participants with more severe DLs of aesthetic concern compared with light-cured composite resin for bonding brackets (low certainty).

1 finding from 1 review

Patient-used 250 ppm F mouthrinse (100 ppm amine F/150 ppm NaF), daily vs 0 ppm F placebo mouthrinse, daily

Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

The review found no eligible studies for this question.

1 finding from 1 review

Professionally-applied 12,300 ppm F APF foam, every 2 months vs 0 ppm F placebo foam

Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

The review found no eligible studies for this question.

1 finding from 1 review