What do systematic reviews say?

Pharmacologic intervention vs placebo

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Pharmacologic intervention vs another pharmacologic intervention

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 participants
  GRADE not reported

Brief intervention vs brief advice, information, or assessment only

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  17 studies · 3913 participants
  Very low
• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1349 participants
  Very low

Brief intervention vs brief advice, information, or assessment only

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 5380 participants
  Very low

Other psychosocial intervention vs usual care, brief intervention, or wait list

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 2106 participants
  Very low

Other psychosocial intervention vs usual care, brief intervention, or wait list

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 1664 participants
  Very low

Pharmacologic intervention vs placebo

Pharmacologic intervention showed no clear difference in retention compared with placebo (low certainty).

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  RR 1.13 [0.89, 1.44]
  3 studies · 247 participants
  Low

Any Psychosocial intervention plus pharm vs psychosocial interventions

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 475 participants
  Low
• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  RR 0.62 [0.16, 2.47]
  1 study · 102 participants
  Very low

Any Psychosocial intervention plus pharm vs psychosocial interventions

Pharmacologic intervention along with psychosocial intervention showed no clear difference in retention compared with psychosocial intervention alone (moderate certainty).

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  RR 1.15 [0.95, 1.4]
  3 studies · 363 participants
  Moderate

Pharmacologic intervention vs another pharmacologic intervention

The review found no eligible studies for this question.

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pharmacologic intervention vs another pharmacologic intervention

Pharmacologic intervention showed no clear difference in retention compared with another pharmacologic intervention (low certainty).

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  RR 0.95 [0.76, 1.19]
  2 studies · 190 participants
  Low
• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  RR 1.02 [0.96, 1.08]
  2 studies · 200 participants
  Low