Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

143 questions · 151 findings · 35 reviews · Headline outcomes only

No studies found 19 · 12.6%GRADE not reported 30 · 19.9%Very low 27 · 17.9%Low 39 · 25.8%Moderate 33 · 21.9%High 3 · 2%

Longer vs shorter duration of combination nicotine replacement therapy

Smoking cessation ‐ 16 weeks versus 8 weeks · people who smoke

It is very uncertain whether longer changes smoking cessation ‐ 16 weeks versus 8 weeks compared with shorter duration of combination nicotine replacement therapy (very low certainty).

1 finding from 1 review

Longer vs shorter duration of combination nicotine replacement therapy

SAEs · people who smoke

It is very uncertain whether longer changes overall SAEs ‐ 26 weeks versus 8 weeks compared with shorter duration of combination nicotine replacement therapy (very low certainty).

3 findings from 1 review

Longer self‐certification vs shorter self‐certification

CBA: Average duration of sickness absence periods in days · workers
2 findings from 1 review

Longer self‐certification vs shorter self‐certification

CBA: Number of sickness absence periods per worker · workers
2 findings from 1 review

Longer self‐certification vs shorter self‐certification

CBA: Average lost work time per 100 person‐years · workers
2 findings from 1 review