Number of ulcer-free days and number of new ulcers · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
A single trial at high risk of bias (Kolseth 2005) randomised participants to the herbal component of LongoVital alone or LongoVital with herbal plus vitamin component. Data presented as medians with 95% CIs,…
1 study · 40 participants
GRADE not reported
Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Early childhood caries (ECC) - incidence/risk · Children with exclusively primary dentition (age ≤71 months)
Breastfeeding beyond 24 months is associated with an increased risk (incidence) of early childhood caries versus not breastfeeding at the same age (RR 2.44, 95% CI 1.97 to 3.02; low certainty).
1 finding from 1 review
Annual increment in DMFS (D3) · Children and adolescents with permanent dentition
Not adjusted meta-regression beta was 0.43 per additional follow-up year.
5 findings from 1 review
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Not adjusted
Meta-regression beta per year of follow-up 0.43 [0.04, 0.83]
22 studies · 11300 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for bitewings and age at baseline
Meta-regression beta per year of follow-up 0.64 [0.31, 0.96]
22 studies · 11300 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for bitewings age at baseline and baseline caries experience
Meta-regression beta per year of follow-up 0.37 [0.04, 0.70]
22 studies · 11300 participants
GRADE not reported
Show 2 more findings
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for groups 1-4 including relevance of evidence and risk of bias
Meta-regression beta per year of follow-up 0.46 [0.08, 0.83]
22 studies · 11300 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for groups 1-3 including decade and preventive intervention
Meta-regression beta per year of follow-up 0.36 [-0.02, 0.73]
22 studies · 11300 participants
GRADE not reported
Annual increment in DMFT (D3) · Children and adolescents with permanent dentition
Not adjusted meta-regression beta was 0.18 per additional follow-up year.
5 findings from 1 review
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Not adjusted
Meta-regression beta per year of follow-up 0.18 [-0.04, 0.40]
13 studies · 24753 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for bitewings and age at baseline
Meta-regression beta per year of follow-up 0.18 [0.02, 0.35]
13 studies · 24753 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for bitewings age at baseline and baseline caries experience
Meta-regression beta per year of follow-up 0.23 [0.06, 0.40]
13 studies · 24753 participants
GRADE not reported
Show 2 more findings
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for groups 1-4 including relevance of evidence and risk of bias
Meta-regression beta per year of follow-up -0.04 [-0.34, 0.26]
13 studies · 24753 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for groups 1-3 including decade and preventive intervention
Meta-regression beta per year of follow-up 0.07 [-0.24, 0.39]
13 studies · 24753 participants
GRADE not reported
Caries incidence rate per person-year at risk (D3) · Children and adolescents with permanent dentition
Adjusted for groups 1-4 including relevance of evidence and risk of bias meta-regression beta was -0.02 per additional follow-up year.
5 findings from 1 review
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for groups 1-4 including relevance of evidence and risk of bias
Meta-regression beta per year of follow-up -0.02 [-0.05, 0.01]
15 studies · 10768 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for bitewings age at baseline and baseline caries experience
Meta-regression beta per year of follow-up 0.00 [-0.00, 0.01]
15 studies · 10768 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for bitewings and age at baseline
Meta-regression beta per year of follow-up 0.00 [-0.00, 0.01]
15 studies · 10768 participants
GRADE not reported
Show 2 more findings
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for groups 1-3 including decade and preventive intervention
Meta-regression beta per year of follow-up -0.00 [-0.02, 0.02]
15 studies · 10768 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Not adjusted
Meta-regression beta per year of follow-up -0.00 [-0.01, 0.01]
15 studies · 10768 participants
GRADE not reported
General degree of discomfort · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
LongoVital (herbal component alone) showed no clear difference in general degree of discomfort compared with placebo; GRADE not reported.
1 finding from 1 review
Number of days of pain (monthly average) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
LongoVital (herbal component alone) showed no clear difference in number of days of pain (monthly average) compared with placebo; GRADE not reported.
1 finding from 1 review
Mean size of ulcers · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
LongoVital (herbal component alone) showed no clear difference in mean size of ulcers compared with placebo; GRADE not reported.
1 finding from 1 review
Number of days of ulcers (monthly average) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
LongoVital (herbal component alone) showed no clear difference in number of days of ulcers (monthly average) compared with placebo; GRADE not reported.
1 finding from 1 review
Number of ulcer-free days and number of new ulcers · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Kolseth 2005 (high risk of bias): 40 patients randomised to the herbal component of LongoVital alone or placebo; data presented as medians with 95% CIs, unsuitable for further analysis; no statistically significant…
1 study · 40 participants
GRADE not reported
Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Salivary flow rate (unstimulated) · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth
codex
1 finding from 1 review
Number of ulcer-free days and number of new ulcers · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Forty patients were randomised to receive LongoVital (herbal plus vitamin) or placebo (Kolseth 2005). Data presented as medians with 95% confidence intervals, unsuitable for further analysis. The authors report no…
1 study · 40 participants
GRADE not reported
Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure
In the high-risk-study-excluded sensitivity meta-regression, longer follow-up was associated with lower success.
1 finding from 1 review
Patient satisfaction · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the maxillary sinus
1 finding from 1 review
Treatment costs · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the maxillary sinus
The review found no eligible studies for this question.
1 finding from 1 review
Treatment costs: no trials reported this outcome (extrapolated by the review authors). Additional costs were associated with the long-implant + augmentation group (extra surgery, biomaterial, barrier, hospitalisation…
0 studies
No studies found
Patient preference · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the maxillary sinus
1 finding from 1 review
Complications (at treated sites) · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the maxillary sinus
Maxillary sinus lift (augmentation) with long implants may leads to higher complications (at treated sites) compared with short implants (5 to 8.5 mm) without sinus augmentation (low certainty).
1 finding from 1 review