Incidence of pain with lidocaine pretreatment Pain scales · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide
Lidocaine may leads to lower pain ‐ lidocaine compared with placebo (low certainty).
1 finding from 1 review
Duration of anaesthesiaTime perioda · patients with digital nerve blocks
1 finding from 1 review
Adverse outcomes · patients with digital nerve blocks
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cost analysis · patients with digital nerve blocks
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Duration of postoperative pain relief · patients with digital nerve blocks
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Bleeding during surgerySubjective assessmentd · patients with digital nerve blocks
Lidocaine may leads to lower bleeding during surgerySubjective assessmentd compared with lidocaine with adrenaline (low certainty).
1 finding from 1 review
Adverse events (e.g. the number of participants that died, or had arrhythmias, other heart rate disorders, or showed any signs of lidocaine toxicity) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Adverse events (e.g. the number of participants that died, or had arrhythmias, other heart rate disorders, or showed any signs of lidocaine toxicity) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Pain with dilation (10 mL 2% lidocaine)a,b · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an early pregnancy loss)
1 finding from 1 review
Pain with dilation (20 mL 1% lidocaine)d,e · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an early pregnancy loss)
1 finding from 1 review
Pain with aspiration (lidocaine)a,b · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an early pregnancy loss)
1 finding from 1 review
Pain with aspiration (20 mL 1% lidocaine)d,e · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an early pregnancy loss)
1 finding from 1 review
Sore throat · patients presenting with postoperative sore throat
lidocaine may leads to lower risk of sore throat 12 hours to 30 hours after the operation compared with control (air/saline) (low certainty).
2 findings from 1 review
All‐cause mortality · patients with acute myocardial infarction
Lidocaine showed no clear difference in all‐cause mortality compared with placebo or no intervention (low certainty).
1 finding from 1 review
Overall survival at 30 days after myocardial infarction · patients with myocardial infarction
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Ventricular fibrillation · patients with myocardial infarction
It is very uncertain whether lidocaine changes ventricular fibrillation compared with disopyramide (very low certainty).
1 finding from 1 review
Adverse events (AEs; adverse drug reaction): asystole · patients with myocardial infarction
It is very uncertain whether lidocaine changes adverse events (AEs; adverse drug reaction): asystole compared with disopyramide (very low certainty).
1 finding from 1 review
Adverse events (AEs; adverse drug reaction): sinoatrial block · patients with myocardial infarction
It is very uncertain whether lidocaine changes adverse events (AEs; adverse drug reaction): sinoatrial block compared with disopyramide (very low certainty).
1 finding from 1 review
Adverse events (AEs; adverse drug reaction): cardiac blocks (high‐degree atrioventricular block and bundle) · patients with myocardial infarction
It is very uncertain whether lidocaine changes adverse events (AEs; adverse drug reaction): cardiac blocks… compared with disopyramide (very low certainty).
1 finding from 1 review
All‐cause mortality · patients with myocardial infarction
It is very uncertain whether lidocaine changes all‐cause mortality compared with tocainide (very low certainty).
1 finding from 1 review