Lidocaine vs placebo or no intervention: All‐cause mortality
- Population
- patients with acute myocardial infarction
- Intervention
- Lidocaine
- Comparison
- placebo or no intervention
- Outcome
- All‐cause mortality
Lidocaine showed no clear difference in all‐cause mortality compared with placebo or no intervention (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Lidocaine vs placebo or no intervention All‐cause mortality · patients with acute myocardial infarction Lidocaine showed no clear difference in all‐cause mortality compared with placebo or no intervention (low certainty). Prophylactic lidocaine for myocardial infarction (2015) · Cochrane Headline outcomes only | RR 1.02 [0.85, 1.27] | 18 studies · 11727 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Prophylactic lidocaine for myocardial infarction 2015 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.