Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

26 questions · 27 findings · 4 reviews · Endodontics and dental trauma

No studies found 12 · 44.4%GRADE not reported 5 · 18.5%Very low 10 · 37%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Thymosin alpha 1 (10-minute soak prior to replantation) vs Normal saline

Tooth survival · People with avulsed and replanted permanent (front) teeth

It is very uncertain whether thymosin alpha 1 (10-minute soak prior to replantation) changes tooth survival at 12 months compared with control (saline) (very low certainty).

2 findings from 1 review

Ledermix root canal medicament (day 0 to 10) vs Ultracal root canal medicament (day 7 to 10)

Aesthetics (discolouration) at 12 months (patient level) · People with avulsed and replanted permanent (front) teeth

It is very uncertain whether ledermix root canal medicament (day 0 to 10) changes aesthetics (discolouration) at 12 months (patient level) compared with ultracal root canal medicament (day 7 to 10) (very low certainty).

1 finding from 1 review

Ledermix root canal medicament (day 0 to 10) vs Ultracal root canal medicament (day 7 to 10)

Tooth survival · People with avulsed and replanted permanent (front) teeth
1 finding from 1 review

Extra-oral pulp extirpation at day 0 vs Intra-oral pulp extirpation at day 7

Radiographic resorption (proxy measure for periodontal healing) at 12 months · People with avulsed and replanted permanent (front) teeth

It is very uncertain whether extra-oral pulp extirpation at day 0 changes radiographic resorption (proxy measure for periodontal healing) at… compared with intra-oral pulp extirpation at day 7 (very low certainty).

1 finding from 1 review

Hyperbaric oxygen (following replantation) vs control

Pulpal healing at 12 months · People with avulsed and replanted permanent (front) teeth

It is very uncertain whether hyperbaric oxygen (following replantation) changes pulpal healing at 12 months compared with control (very low certainty).

1 finding from 1 review

Hyperbaric oxygen (following replantation) vs control

Periodontal healing at 12 months · People with avulsed and replanted permanent (front) teeth

It is very uncertain whether hyperbaric oxygen (following replantation) changes periodontal healing at 12 months compared with control (very low certainty).

1 finding from 1 review

Thymosin alpha 1 (10-minute soak prior to replantation) vs Normal saline

Periodontal healing at 48 months · People with avulsed and replanted permanent (front) teeth

It is very uncertain whether thymosin alpha 1 (10-minute soak prior to replantation) changes periodontal healing at 48 months compared with control (saline) (very low certainty).

1 finding from 1 review

Ledermix root canal medicament (day 0 to 10) vs Ultracal root canal medicament (day 7 to 10)

Periodontal healing at 12 months · People with avulsed and replanted permanent (front) teeth

It is very uncertain whether ledermix root canal medicament (day 0 to 10) changes periodontal healing at 12 months (tooth level) compared with ultracal root canal medicament (day 7 to 10) (very low certainty).

1 finding from 1 review

Repositioning of ankylosed teeth after osteotomy followed or not by distraction osteogenesis, or after luxation vs Conventional orthodontic treatment or follow-up with no specific treatment for ankylosis

Outcome not reported · Any patient with ankylosis and displacement of permanent front teeth diagnosed by clinical and radiographic assessment, with or without…

The review found no eligible studies for this question.

1 finding from 1 review

Root canal medications and canal filling, splinting, extraction of teeth, or surgical removal of any relevant pathology vs Each other, placebo, or no treatment

Outcome not reported · Patients with single and multiple permanent teeth with evidence of any type of external root resorption irrespective of its aetiology,…

The review found no eligible studies for this question.

1 finding from 1 review
  • Interventions for the management of external root resorption 2015 · Cochrane All outcomes
    Any follow-up period
    None of the studies fulfilled our inclusion criteria and therefore no data analysis was conducted. (Main results: no RCTs that met the inclusion criteria were identified; one ongoing study, NCT00423956, potentially…
    0 studies
    No studies found

Transplantation of other teeth after extraction of the ankylosed teeth vs Conventional orthodontic treatment or follow-up with no specific treatment for ankylosis

Outcome not reported · Any patient with ankylosis and displacement of permanent front teeth diagnosed by clinical and radiographic assessment, with or without…

The review found no eligible studies for this question.

1 finding from 1 review