Question · asked by 1 review

Thymosin alpha 1 (10-minute soak prior to replantation) vs Normal saline: Adverse effects

Population
People with avulsed and replanted permanent (front) teeth
Intervention
Thymosin alpha 1 (10-minute soak prior to replantation)
Comparison
Normal saline
Outcome
Adverse effects

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Thymosin alpha 1 (10-minute soak prior to replantation) vs Control (saline)
Adverse effects · People with avulsed and replanted permanent (front) teeth
Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted (2019) · Cochrane All outcomes
Loo 2008 did not report this outcome; following email correspondence, authors reported no adverse effects were seen (uncertain whether formally assessed).1 studyGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted
2019 · Cochrane All outcomes
2018-03Not listedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.