Adverse events: AMD progression at 12 months Defined as increased drusen volume or onset of advanced AMD. Conversion to exudative AMD at 12 months Assessed by clinical examination and retinal optical coherence tomography. · people with non‐exudative AMD (AREDS 2 to 4)
Photobiomodulation treatment showed no clear difference in adverse events: AMD progression at 12 months Defined as increased… compared with sham or no treatment (low certainty).
1 finding from 1 review
RR 0.79 [0.41, 1.53]
Studies not reported
Low
Proportion of participants whose maximum K increased by at least 2 diopters—at 24 months · participants with progressive keratoconus
It is very uncertain whether transepithelial CXL using iontophoresis changes proportion of participants whose maximum K increased by at least 2… compared with epithelium‐off CXL (very low certainty).
1 finding from 1 review
Proportion of participants whose maximum K increased by at least 2 diopters—at 12 months · participants with keratoconus
It is very uncertain whether transepithelial CXL changes proportion of participants whose maximum K increased by at least 2… compared with epithelium‐off CXL (very low certainty).
1 finding from 1 review
IOP increase of ≥ 5 mmHg within 2 hours · people with glaucoma receiving LTP
1 finding from 1 review
Mean change in IOP from pre‐LTP within 2 hours · people with glaucoma receiving LTP
1 finding from 1 review
IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mean change in IOP from pre‐LTP between 2 and 24 hours · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events during treatment period · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
IOP increase of ≥ 5 mmHg within 2 hours · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
IOP increase of ≥ 10 mmHg within 2 hours · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mean change in IOP from pre‐LTP within 2 hours · people with glaucoma receiving LTP
1 finding from 1 review
IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP
1 finding from 1 review
no estimate extracted
Studies not reported
Low
IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP
Apraclonidine showed no clear difference in IOP increase of ≥ 10 mmHg between 2 and 24 hours compared with pilocarpine (low certainty).
1 finding from 1 review
IOP increase of ≥ 10 mmHg within 2 hours · people with glaucoma receiving LTP
Medication probably leads to lower IOP increase of ≥ 10 mmHg within 2 hours compared with placebo (moderate certainty).
1 finding from 1 review
Mean change in IOP from pre‐LTP between 2 and 24 hours · people with glaucoma receiving LTP
1 finding from 1 review
Adverse events during treatment period · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
IOP increase of ≥ 5 mmHg within 2 hours · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
IOP increase of ≥ 10 mmHg within 2 hours · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mean change in IOP from pre‐LTP within 2 hours · people with glaucoma receiving LTP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found