Clinically‐diagnosed sepsis Clinical, biochemical and/or microbiological methods · Adult patients who required central venous catheters
Impregnated catheters showed no clear difference in clinically‐diagnosed sepsis Identified by clinical, biochemical… compared with non‐impregnated catheters (moderate certainty).
1 finding from 1 review
Catheter‐related blood stream infection · Adult patients who required central venous catheters
Impregnated catheters leads to lower catheter‐related blood stream infection (CRBSI) Identified by… compared with non‐impregnated catheters (high certainty).
1 finding from 1 review
All‐cause mortality · Adult patients who required central venous catheters
Impregnated catheters showed no clear difference in all‐cause mortality compared with non‐impregnated catheters (high certainty).
1 finding from 1 review
Catheter colonization Catheter culture (microbiological methods) · Adult patients who required central venous catheters
Impregnated catheters probably leads to lower catheter colonization Identified by catheter culture… compared with non‐impregnated catheters (moderate certainty).
1 finding from 1 review
Catheter‐related local infection Catheter culture (microbiological methods) and clinical features · Adult patients who required central venous catheters
Impregnated catheters showed no clear difference in catheter‐related local infection Identified by catheter culture… compared with non‐impregnated catheters (moderate certainty).
1 finding from 1 review
Adverse effects (combined) Clinical assessment · Adult patients who required central venous catheters
Impregnated catheters showed no clear difference in adverse effects (combined) Identified by clinical assessment compared with non‐impregnated catheters (high certainty).
1 finding from 1 review
Number of participants experiencing shunt infection after implantation of antibiotic impregnated catheters · CSF‐shunt infections
It is very uncertain whether antibiotic prophylaxis changes number of participants experiencing shunt infection after… compared with no antibiotic prophylaxis / standard care (very low certainty).
1 finding from 1 review
Catheter‐related blood stream infection · patients with CVCs
Medication‐impregnated dressings leads to lower catheter‐related blood stream infection compared with all other dressing types (high certainty).
1 finding from 1 review
Urinary sepsis · Patients with an indwelling urethral catheter of short‐term duration
1 finding from 1 review
Patient discomfort whilst catheter is in situ · Patients with an indwelling urethral catheter of short‐term duration
1 finding from 1 review
Symptomatic CAUTI: without microbiological evidence ‐ antibiotic versus silver alloy · Patients with an indwelling urethral catheter of short‐term duration
Antimicrobial‐impregnated catheter showed no clear difference in symptomatic CAUTI: without microbiological evidence ‐ antibiotic… compared with antiseptic‐coated catheter (moderate certainty).
1 finding from 1 review
Bacterial resistance towards the antimicrobial agent ‐ not reported · Patients with an indwelling urethral catheter of short‐term duration
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Symptomatic CAUTI: with microbiological evidence ‐ antibiotic versus silver alloy · Patients with an indwelling urethral catheter of short‐term duration
Antimicrobial‐impregnated catheter leads to lower symptomatic CAUTI: with microbiological evidence ‐ antibiotic versus… compared with antiseptic‐coated catheter (high certainty).
1 finding from 1 review
Urinary sepsis · Patients with an indwelling urethral catheter of short‐term duration
1 finding from 1 review
Patient discomfort whilst catheter is in situ · Patients with an indwelling urethral catheter of short‐term duration
Antimicrobial‐impregnated catheter leads to higher patient discomfort whilst catheter is in situ compared with antiseptic‐coated catheter (high certainty).
1 finding from 1 review
Symptomatic CAUTI: without microbiological evidence ‐ nitrofurazone versus standard · Patients with an indwelling urethral catheter of short‐term duration
1 finding from 1 review
Symptomatic CAUTI: with microbiological evidence ‐ nitrofurazone versus standard · Patients with an indwelling urethral catheter of short‐term duration
1 finding from 1 review
Bacterial resistance towards the antimicrobial agent ‐ not reported · Patients with an indwelling urethral catheter of short‐term duration
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Catheter‐related blood stream infection · patients with CVCs
Chlorhexidine gluconate‐impregnated (CGI) dressing showed no clear difference in catheter‐related blood stream infection compared with SPU dressings (moderate certainty).
1 finding from 1 review
Catheter tip colonisation · patients with CVCs
Chlorhexidine gluconate‐impregnated (CGI) dressing probably leads to lower catheter tip colonisation: compared with SPU dressings (moderate certainty).
1 finding from 1 review