What do systematic reviews say?

Dextrose gel vs control

Oral dextrose gel showed no clear difference in correction of hypoglycaemia for each hypoglycaemic event before… compared with control (moderate certainty).

• Oral dextrose gel for the treatment of hypoglycaemia in newborn infants 2022 · Cochrane Headline outcomes only
  Rate ratio 1.08 [0.98, 1.2]
  1 study · 237 participants
  Moderate

Dextrose gel vs control

It is very uncertain whether oral dextrose gel changes receipt of intravenous treatment for hypoglycaemia before discharge… compared with control (very low certainty).

• Oral dextrose gel for the treatment of hypoglycaemia in newborn infants 2022 · Cochrane Headline outcomes only
  RR 0.78 [0.46, 1.32]
  2 studies · 312 participants
  Very low

Dextrose gel vs control

• Oral dextrose gel for the treatment of hypoglycaemia in newborn infants 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 237 participants
  Low

Dextrose gel vs control

Oral dextrose gel probably leads to lower separation from mother for treatment of hypoglycaemia before… compared with control (moderate certainty).

• Oral dextrose gel for the treatment of hypoglycaemia in newborn infants 2022 · Cochrane Headline outcomes only
  RR 0.54 [0.31, 0.93]
  1 study · 237 participants
  Moderate

Oropharyngeal colostrum (OPC) vs No treatment or saline or water

It is very uncertain whether oropharyngeal colostrum (OPC) changes death before discharge to home compared with control (water, saline, or no intervention) (very low certainty).

• Oropharyngeal colostrum in preventing mortality and morbidity in preterm infants 2018 · Cochrane Headline outcomes only
  RR 0.76 [0.34, 1.71]
  6 studies · 335 participants
  Very low

Transfer from incubator to cot at lower vs higher body weight

• Transfer of preterm infants from incubator to open cot at lower versus higher body weight 2011 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 276 participants
  High

Intervention not reported

The intervention showed no clear difference in neonatal mortality (low certainty).

• Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
  RR 0.2 [0.01, 4.03]
  1 study · 202 participants
  Low

Intervention not reported

The intervention probably leads to lower infections (moderate certainty).

• Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
  RR 0.69 [0.49, 0.95]
  1 study · 203 participants
  Moderate

Intervention not reported

The intervention leads to lower neonatal mortality (high certainty).

• Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
  RR 0.81 [0.71, 0.92]
  3 studies · 31084 participants
  High

Intervention not reported

The intervention leads to lower omphalitis (high certainty).

• Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
  RR 0.48 [0.4, 0.57]
  3 studies · 39925 participants
  High

Intervention not reported

The intervention showed no clear difference in neonatal mortality (high certainty).

• Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
  RR 1.03 [0.87, 1.23]
  1 study · 17530 participants
  High

Intervention not reported

• Chlorhexidine skin or cord care for prevention of mortality and infections in neonates 2015 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported