Mean change from baseline in meibomian gland expression scores at 1 to 4 weeks (higher is favored) · people with dry eye
It is very uncertain whether lipiFlow changes mean change from baseline in meibomian gland expression scores at 1… compared with basic warm compresses (very low certainty).
1 finding from 1 review
Mean change from baseline in meibum quality scores at 1 to 4 weeks (higher is favored) · people with dry eye
It is very uncertain whether lipiFlow changes mean change from baseline in meibum quality scores at 1 to 4 weeks… compared with basic warm compresses (very low certainty).
1 finding from 1 review
Mean change from baseline in meibomian gland expression scores at 1 to 4 weeks (higher is favored) · people with dry eye
LipiFlow showed no clear difference in mean change from baseline in meibomian gland expression scores at 1… compared with thermostatic devices (low certainty).
1 finding from 1 review
Mean change from baseline in meibum quality scores at 1 to 4 weeks (higher is favored) · people with dry eye
LipiFlow showed no clear difference in mean change from baseline in meibum quality scores at 1 to 4 weeks… compared with thermostatic devices (low certainty).
1 finding from 1 review
Quality of life assessments at 3 months or later (higher is favored) · people with primary macula‐involving rhegmatogenous retinal detachments
It is very uncertain whether face‐down positioning changes quality of life assessments at 3 months or later (higher is favored) compared with other positioning (very low certainty).
1 finding from 1 review
Visual acuity · proliferative diabetic retinopathy
1 finding from 1 review
Intervention not reported
High‐dose atropine (≥ 0.5%) · children with progressive myopia (38 studies, 6525 participants in analyses) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
Intervention not reported
High‐dose atropine (≥ 0.5%) · children with progressive myopia (26 studies, 4949 participants in the analysis) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
Intervention not reported
High‐dose atropine (≥ 0.5%) · children with progressive myopia (36 studies, 6263 participants) in the analysis Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
Intervention not reported
High‐dose atropine (≥ 0.5%) · children with progressive myopia (21 studies, 4169 participants in the analysis) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
Proportion of participants with IOP control (higher number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure
Phacoemulsification may leads to higher proportion of participants with IOP control (higher number of events… compared with laser peripheral iridotomy (low certainty).
1 finding from 1 review
Mean change in VAS (higher scores suggest greater disease activity and worse quality of life) at ≥ 12 months · adults aged over 50 years with giant cell arteritis
Tocilizumab weekly showed no clear difference in mean change in VAS (higher scores suggest greater disease activity… compared with placebo + 52‐week taper (moderate certainty).
1 finding from 1 review
Mean change in VAS (higher scores suggest greater disease activity and worse quality of life) at ≥ 12 months · adults aged over 50 years with giant cell arteritis
Tocilizumab weekly showed no clear difference in mean change in VAS (higher scores suggest greater disease activity… compared with placebo + 26‐week taper (moderate certainty).
1 finding from 1 review
Mean change in VAS (higher scores suggest greater disease activity and worse quality of life) at ≥ 12 months · adults aged over 50 years with giant cell arteritis
Tocilizumab every other week showed no clear difference in mean change in VAS (higher scores suggest greater disease activity… compared with placebo + 52‐week taper (moderate certainty).
1 finding from 1 review
Mean change in VAS (higher scores suggest greater disease activity and worse quality of life) at ≥ 12 months · adults aged over 50 years with giant cell arteritis
Tocilizumab every other week showed no clear difference in mean change in VAS (higher scores suggest greater disease activity… compared with placebo + 26‐week taper (moderate certainty).
1 finding from 1 review
Mean change in VAS (higher scores suggest greater disease activity and worse quality of life) at ≥ 12 months · adults aged over 50 years with giant cell arteritis
The review found no eligible studies for this question.
1 finding from 1 review
Resolution of symptoms · epidemic keratoconjunctivitis
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Proportion of participants with resolution of signs within 7 days of treatment (higher is favored) · epidemic keratoconjunctivitis
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Proportion of participants in whose eyes SEI had disappeared within 21 days of treatment (higher is favored) · epidemic keratoconjunctivitis
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Proportion of participants who discontinued medication and did not develop rebound SEI within 21 days (higher is favored) · epidemic keratoconjunctivitis
It is very uncertain whether any intervention changes proportion of participants who discontinued medication and did not… compared with steroid alone or plus levofloxacin (very low certainty).
1 finding from 1 review