Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

32 questions · 32 findings · 5 reviews

No studies found 4 · 12.5%GRADE not reported 0 · 0%Very low 24 · 75%Low 3 · 9.4%Moderate 1 · 3.1%High 0 · 0%

Helium vs carbon dioxide

Pneumoperitoneum‐related serious adverse events · people undergoing laparoscopic general abdominal or gynaecological pelvic surgery under general anaesthesia

It is very uncertain whether helium changes pneumoperitoneum‐related serious adverse events compared with carbon dioxide (very low certainty).

1 finding from 1 review

Helium vs carbon dioxide

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people undergoing laparoscopic general abdominal or gynaecological pelvic surgery under general anaesthesia

Helium showed no clear difference in pain scores (first postoperative day) Visual analogue scale, lower… compared with carbon dioxide (low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Scar severity ‐ Helium‐Neon (He‐Ne) laser plus decamethyltetrasiloxane, polydimethylsiloxane and cyclopentasiloxane cream versus decamethyltetrasiloxane, polydimethylsiloxane and cyclopentasiloxane cream ‐ Vancouver Scar scale (VSS) (higher scores... · participants with hypertrophic and keloid scars
1 finding from 1 review

Transepithelial CXL using iontophoresis vs epithelium‐off CXL

Proportion of participants whose maximum K decreased by at least 2 diopters—at 24 months · participants with progressive keratoconus

It is very uncertain whether transepithelial CXL using iontophoresis changes proportion of participants whose maximum K decreased by at least 2… compared with epithelium‐off CXL (very low certainty).

1 finding from 1 review

Transepithelial CXL using iontophoresis vs epithelium‐off CXL

Proportion of participants whose maximum K increased by at least 2 diopters—at 24 months · participants with progressive keratoconus

It is very uncertain whether transepithelial CXL using iontophoresis changes proportion of participants whose maximum K increased by at least 2… compared with epithelium‐off CXL (very low certainty).

1 finding from 1 review

Transepithelial CXL using iontophoresis vs epithelium‐off CXL

Proportion of participants whose keratoconus remained stable—at 24 months · participants with progressive keratoconus

It is very uncertain whether transepithelial CXL using iontophoresis changes proportion of participants whose keratoconus remained stable—at 24… compared with epithelium‐off CXL (very low certainty).

1 finding from 1 review