Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

121 questions · 124 findings · 19 reviews · Gynaecology and Fertility

No studies found 40 · 32.3%GRADE not reported 0 · 0%Very low 38 · 30.6%Low 34 · 27.4%Moderate 9 · 7.3%High 3 · 2.4%

Any anti‐adhesion therapy vs anti‐adhesion therapy B following operative hysteroscopy

Presence of intrauterine adhesions at second‐look hysteroscopy (6‐12 weeks) · women treated by operative hysteroscopy for uterine pathology

Any anti‐adhesion therapy A may leads to lower presence of intrauterine adhesions at second‐look hysteroscopy (6‐12… compared with anti‐adhesion therapy B following operative hysteroscopy (low certainty).

1 finding from 1 review

Any anti‐adhesion therapy vs placebo or no treatment following operative hysteroscopy

Presence of intrauterine adhesions at second‐look hysteroscopy (6‐12 weeks) · women treated by operative hysteroscopy for uterine pathology associated with subfertility or adverse pregnancy outcome

Any anti‐adhesion therapy may leads to lower presence of intrauterine adhesions at second‐look hysteroscopy… compared with placebo or no treatment following operative hysteroscopy (low certainty).

1 finding from 1 review

Any anti‐adhesion therapy vs anti‐adhesion therapy B following operative hysteroscopy

Live birth · women treated by operative hysteroscopy for uterine pathology

Any anti‐adhesion therapy A showed no clear difference in live birth a compared with anti‐adhesion therapy B following operative hysteroscopy (low certainty).

1 finding from 1 review

Analysis 7 ‐ Collagen membrane with polyethylene glycol and glycerol vs Ringer's lactate

Incidence of adhesions ‐ de novo Incidence at second‐look laparoscopy · patients with adhesion prevention after gynaecological surgery

Analysis 7 ‐ Collagen membrane with polyethylene glycol and glycerol may leads to lower incidence of adhesions ‐ de novo Incidence at second‐look laparoscopy compared with ringer's lactate (low certainty).

1 finding from 1 review

Any anti‐adhesion therapy vs placebo or no treatment following operative hysteroscopy

Live birth · women treated by operative hysteroscopy for uterine pathology associated with subfertility or adverse pregnancy outcome

It is very uncertain whether any anti‐adhesion therapy changes live birth a compared with placebo or no treatment following operative hysteroscopy (very low certainty).

1 finding from 1 review

Analysis 1 ‐ Oxidised regenerated cellulose vs no treatment at laparotomy

Incidence of adhesions ‐ de novo Incidence at second‐look laparoscopy · women having gynaecological surgery

It is very uncertain whether analysis 2 ‐ Oxidised regenerated cellulose changes incidence of adhesions ‐ de novo Incidence at second‐look laparoscopy compared with no treatment at laparotomy (very low certainty).

1 finding from 1 review