Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

23 questions · 32 findings · 5 reviews

No studies found 6 · 18.8%GRADE not reported 0 · 0%Very low 7 · 21.9%Low 14 · 43.8%Moderate 5 · 15.6%High 0 · 0%

GnRHa treatment vs placebo or no pretreatment

Operating time · women with uterine fibroids
3 findings from 1 review

GnRHa treatment vs placebo or no pretreatment

Intraoperative blood loss (mL) · women with uterine fibroids
3 findings from 1 review

GnRHa treatment vs placebo or no pretreatment

Blood transfusion · women with uterine fibroids

GnRHa treatment showed no clear difference in blood transfusions compared with no pretreatment or placebo before myomectomy (operative and… (low certainty).

3 findings from 1 review

GnRHa treatment vs placebo or no pretreatment

Overall postoperative morbidity · women with uterine fibroids

GnRHa treatment showed no clear difference in postoperative morbidity compared with no pretreatment or placebo before myomectomy (operative and… (low certainty).

3 findings from 1 review

GnRHa treatment vs other medical therapies before any surgery

Preoperative bleeding: (PBAC < 75) ulipristal acetate 5 mg · women with uterine fibroids

GnRHa treatment showed no clear difference in preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal… compared with other medical therapies before any surgery (moderate certainty).

1 finding from 1 review

GnRHa treatment vs other medical therapies before any surgery

Preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal acetate 10 mg · women with uterine fibroids

GnRHa treatment showed no clear difference in preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal… compared with other medical therapies before any surgery (moderate certainty).

1 finding from 1 review

Effect of GnRHas vs other hormonal treatment on bone mineral density

GnRHas vs gestrinone Percentage change values ‐ 12 months · Women with endometriosis, treated with GnRHas with effect on bone mineral density
2 findings from 1 review