Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 5 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 5 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Fibrinogen concentrate vs any comparator

Incidence of allogenic blood transfusion Proportion of participants transfused with RBC, FFP, PLT and/or cryo · bleeding patients or at risk of severe bleeding

It is very uncertain whether fibrinogen concentrate changes incidence of allogenic blood transfusion Proportion of participants… compared with any comparator (very low certainty).

1 finding from 1 review

Fibrinogen concentrate vs any comparator

Thrombotic episodes (arterial and venous graft occlusion, pulmonary embolus, deep venous thrombosis) Proportion with event · bleeding patients or at risk of severe bleeding

It is very uncertain whether fibrinogen concentrate changes thrombotic episodes (arterial and venous graft occlusion, pulmonary… compared with any comparator (very low certainty).

1 finding from 1 review

Fibrinogen concentrate vs any comparator

Re‐operation due to persistent bleeding Events during admission · bleeding patients or at risk of severe bleeding

It is very uncertain whether fibrinogen concentrate changes re‐operation due to persistent bleeding Events during admission compared with any comparator (very low certainty).

1 finding from 1 review