Question · asked by 1 review

Fibrinogen concentrate vs any comparator: All‐cause mortality

It is very uncertain whether fibrinogen concentrate changes mortality compared with any comparator (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Fibrinogen concentrate vs any comparator
Mortality · bleeding patients or at risk of severe bleeding
It is very uncertain whether fibrinogen concentrate changes mortality compared with any comparator (very low certainty).
Fibrinogen concentrate in bleeding patients (2013) · Cochrane Headline outcomes only
RR 0.28 [0.03, 2.33]2 studies · 81 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Fibrinogen concentrate in bleeding patients
2013 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.