Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

188 questions · 189 findings · 28 reviews · Headline outcomes only

No studies found 56 · 29.6%GRADE not reported 4 · 2.1%Very low 39 · 20.6%Low 49 · 25.9%Moderate 36 · 19%High 5 · 2.6%

ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs usual care

Family outcome: Burden ‐ not improved/worse (objective burden related to self‐sufficiency) · patients with schizophrenia

It is very uncertain whether ANY FAMILY BASED INTERVENTIONS (>5 sessions) changes family outcome: Burden ‐ not improved/worse (objective burden… compared with STANDARD CARE (very low certainty).

1 finding from 1 review

ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs usual care

Social functioning: Specific ‐ unemployed ‐ at about 1 year · patients with schizophrenia

ANY FAMILY BASED INTERVENTIONS (>5 sessions) showed no clear difference in social functioning: Specific ‐ unemployed ‐ at about 1 year compared with STANDARD CARE (low certainty).

1 finding from 1 review

ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs usual care

Social functioning: Specific ‐ unable to live independently ‐ at about 1 year · patients with schizophrenia

ANY FAMILY BASED INTERVENTIONS (>5 sessions) showed no clear difference in social functioning: Specific ‐ unable to live independently ‐ at… compared with STANDARD CARE (low certainty).

1 finding from 1 review

Family therapy vs psychological interventions

Remission

It is very uncertain whether family therapy changes remission post‐intervention compared with psychological interventions (very low certainty).

2 findings from 1 review